Evidence map›Paper›PMID 40852430›Full record

ArticleFrontiers in veterinary science2025

Heat stress on sperm quality in dogs: effect of natural antioxidant supplementation.

Lucrezia Forte, Matteo Burgio, Annalisa Rizzo, Aristide Maggiolino, Alice Carbonari, Pasquale De Palo, Giovanni Michele Lacalandra, Vincenzo Cicirelli

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. FeedingVeterinary and animal science · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Impact of Oxidative Stress and Antioxidants on Semen Quality in Dogs.Animals : an open access journal from MDPI · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lucrezia ForteDepartment of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Matteo BurgioDepartment of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Annalisa RizzoDepartment of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Aristide MaggiolinoDepartment of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Alice CarbonariDepartment of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Pasquale De PaloDepartment of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Giovanni Michele LacalandraDepartment of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Vincenzo CicirelliDepartment of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Heat stress negatively affects canine reproductive health by inducing oxidative stress and impairing sperm quality. This study assessed the efficacy of a polyphenolic extract from Loblolly pine ( Methods: Forty clinically healthy male dogs were divided into two groups: a control (CON) group receiving a standard diet and a PTHL-supplemented group for 90 days. During summer, dogs were exposed to natural heat stress, and key parameters, including serum biochemical markers, oxidative stress indicators, antioxidant enzyme activity, and sperm quality were evaluated. Mixed-effects models analyzed group, time, and interaction effects. Results and discussion: PTHL supplementation significantly reduced plasma TBARS and seminal d-ROMs levels ( Conclusion: These findings suggest that PTHL enhances antioxidant defenses, mitigating heat stress-induced reproductive impairment. This natural strategy may improve fertility in dogs facing environmental challenges. Future studies should explore different dosages and extended supplementation to optimize its benefits.

Indexed as

antioxidantsbiochemical profiledogssemen qualitythermal stress

Identifiers

PMID40852430
PMCPMC12368504

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.