Evidence map›Paper›PMID 40852186›Full record

ArticleFrontiers in endocrinology2025

Association of wrist circumference with metabolic dysfunction associated fatty liver disease in the KADEM cohort.

Fahad Al-Ajmi, Mohamed Abu-Farha, Ahmed N Albatineh, Zahraa Ali, Abdullah Al-Enezi, Mohammed Alterki, Rashed Alhammad, Retaj AlHarbi, Mohamed Shehab, Muhammad Abdul-Ghani and 2 more

Abstract read
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Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fahad Al-Ajmi *Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman, Kuwait.
Mohamed Abu-Farha *Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman, Kuwait.
Ahmed N AlbatinehDepartment of Biostatistics and Health Data Science, College of Health, Lehigh University, Bethlehem, PA, United States.
Zahraa AliDepartment of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman, Kuwait.
Abdullah Al-EneziDepartment of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman, Kuwait.
Mohammed AlterkiDepartment of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman, Kuwait.
Rashed AlhammadDepartment of Pharmacology, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.
Retaj AlHarbiDepartment of Translational Research, Dasman Diabetes Institute, Dasman, Kuwait.
Mohamed ShehabDepartment of Translational Research, Dasman Diabetes Institute, Dasman, Kuwait.
Muhammad Abdul-GhaniDepartment of Translational Research, Dasman Diabetes Institute, Dasman, Kuwait.
Jehad AbubakerDepartment of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman, Kuwait.
Fahd Al-MullaDepartment of Translational Research, Dasman Diabetes Institute, Dasman, Kuwait.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Metabolic dysfunction-associated fatty liver disease (MAFLD) is linked to metabolic dysfunction and to an increased risk of cardiovascular diseases. The early detection of individuals at high risk of MAFLD is essential for timely interventions. This study explores the association between wrist circumference and MAFLD among participants in the Kuwait Adult Diabetes and Epidemiological Multidisciplinary (KADEM) program, aiming to evaluate wrist circumference as a potential noninvasive diagnostic marker. Materials and methods: This study included 449 participants assessed for MAFLD using FibroScan Results: The cohort included 184 (41.5%) normal, 77 (17.4%) S1, 81 (18.3%) S2, and 101 (22.8%) S3 participants. Wrist circumference was significantly different across groups: 16 cm for normal, 17 cm for S1 and S2, and 17.2 cm for S3 ( Conclusion: Wrist circumference is a potential noninvasive marker for the identification of individuals at high risk of MAFLD, representing a cost-effective screening tool for early detection. Further research is needed to confirm its clinical utility.

Indexed as

Fatty LiverMetabolic DiseasesNon-alcoholic Fatty Liver DiseaseWristAdultAgedBiomarkersBody Mass IndexCohort StudiesFemaleHumansMaleMiddle AgedROC CurveBiomarkersCAPMAFLDobesityT2Dwrist circumference

Identifiers

PMID40852186
PMCPMC12367489

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.