Evidence map›Paper›PMID 40852169›Full record

ArticleSurgical case reports2025

Thymic Amyloidosis Mimicking Thymoma: A Case Report.

Asuka Tomida, Motoki Yano, Tomohiro Setogawa, Ryotaro Katsuya, Chihiro Furuta, Naoki Ozeki, Takayuki Fukui

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Amyloid A Amyloidosis Secondary to Thymoma.Diagnostics (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Asuka TomidaDivision of Chest Surgery, Department of Surgery, Aichi Medical University, Nagakute, Aichi, Japan.
Motoki YanoDivision of Chest Surgery, Department of Surgery, Aichi Medical University, Nagakute, Aichi, Japan.
Tomohiro SetogawaDivision of Chest Surgery, Department of Surgery, Aichi Medical University, Nagakute, Aichi, Japan.
Ryotaro KatsuyaDivision of Chest Surgery, Department of Surgery, Aichi Medical University, Nagakute, Aichi, Japan.
Chihiro FurutaDivision of Chest Surgery, Department of Surgery, Aichi Medical University, Nagakute, Aichi, Japan.
Naoki OzekiDivision of Chest Surgery, Department of Surgery, Aichi Medical University, Nagakute, Aichi, Japan.
Takayuki FukuiDivision of Chest Surgery, Department of Surgery, Aichi Medical University, Nagakute, Aichi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe most common anterior mediastinal tumors are thymic epithelial tumors, including thymoma, and other kinds of diseases are relatively rare. Here, we report our experience in treating a patient with amyloidosis of the thymus, a very rare type of mediastinal lesion. CASE PRESENTATION: We experienced thymic amyloidosis mimicking a thymoma. A 66-year-old male underwent thymectomy for an anterior mediastinal tumor, which was incidentally pointed out with chest CT. The pathological examination revealed that eosinophilic unstructured substances were present around the atrophied thymic tissue, suggesting the presence of amyloid deposits. Thus, the postoperative pathological diagnosis was thymic amyloidosis. Thymic amyloidosis is extremely rare. Since other amyloid deposits were identified in the gastric mucosa of this patient, he was diagnosed with systemic amyloidosis, and chemotherapy was initiated. The patient had no progression of amyloidosis for 21 months after surgery.

conclusionsTo the best of our knowledge, only 8 cases of thymic amyloidosis, including the present case, have been reviewed in the literature. Although thymic amyloidosis is extremely rare, an unfavorable prognosis has occasionally been reported. In addition, thymoma and thymic amyloidosis have similar imaging findings, thus making it difficult to distinguish between them. Therefore, thoracic surgeons may need to be aware that thymic amyloidosis is included in the list of anterior mediastinal lesions.

Indexed as

amyloidosismediastinal tumorthymoma

Identifiers

PMID40852169
PMCPMC12370321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.