ArticleAsian journal of neurosurgery2025
Cocaine-Induced Midline Destructive Lesions-A Harbinger of Meningitis and Hydrocephalus.
Article in Asian journal of neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Cocaine is among the most commonly used recreational drugs in Scotland, contributing to significant socioeconomic and severe health challenges. The prevalence of cocaine-induced midline destructive lesions (CIMDL) is rising due to increased cocaine insufflation. Here, we report a case of a patient who developed acute hydrocephalus and meningitis as complications of CIMDL due to long-term cocaine abuse. A 39-year-old woman with a history of chronic nasal cocaine abuse presented with fever, malaise, and gait imbalance. On arrival at accident and emergency department, she had altered sensorium, Glasgow coma scale (GCS) of 10, and left-sided hemiparesis, requiring emergency intubation. Imaging revealed acute hydrocephalus and brain edema. She underwent an emergency external ventricular drain (EVD) to temporize her raised intracranial pressure. Her constellation of problems and biochemical parameters directed toward a diagnosis of acute bacterial meningitis. Her blood cultures grew methicillin-sensitive
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