ArticleAnnals of medicine and surgery (2012)2025
Tetanus - a lethal and neglected infectious disease.
Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Tailoring educational interventions targeting parental vaccine hesitancy: a systematic review of quantitative studies.Frontiers in public health · 2026Pooled it
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction and importance: Tetanus, caused by Case presentation: A 55-year-old male with a history of alcohol abuse presented with classic tetanus symptoms, including muscle rigidity, trismus, and opisthotonus. Despite intravenous medications and antibiotics, his condition worsened, requiring intubation, mechanical ventilation, and resuscitation for cardiac complications. Unfortunately, due to financial constraints, he left the ICU against medical advice and died shortly after discharge. Clinical discussion: The incidence of tetanus has significantly decreased in affluent nations since the 1940s due to widespread vaccination. From 2009 to 2017, 264 cases were reported in the U.S. Despite global efforts, tetanus remains a public health concern, with the World Health Organization reporting 21,897 cases globally in 2023, reflecting ongoing gaps in prevention, vaccination coverage, and healthcare access. Generalized tetanus, characterized by painful muscle spasms and autonomic dysfunction, is more common than localized or cephalic tetanus. Diagnosis is clinical, and treatment involves wound care, managing spasms, administering anti-tetanus immunoglobulin, and an accelerated immunization regimen for long-term protection. Conclusion: This case highlights the critical need for vigilance and vaccination programs in areas with limited healthcare resources. Tetanus continues to be a major public health concern, and timely interventions, such as intravenous immunoglobulin, can be lifesaving. In developing countries, prioritizing routine vaccination and booster shots is essential to reduce the devastating impact of this preventable disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.