Evidence map›Paper›PMID 40851964›Full record

ReviewAnnals of medicine and surgery (2012)2025

Inflammation in cardio-oncology and psychological disorders: mechanisms, biomarkers, pain management, and therapeutic strategies.

Shreya Singh Beniwal, Daniela Castro Calderón, Tanish Baweja, Sweta Yadav, Kareena Vania, Ashka Priyadarshi, Saakshi Ijantkar, Jana Kotaich

Abstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shreya Singh BeniwalLady Hardinge Medical College, Connaught Place, New Delhi, India.
Daniela Castro CalderónUniversidad Peruana De Ciencias Aplicadas (UPC), Lima, Perú.
Tanish BawejaHamdard Institute of Medical Sciences and Research, New Delhi, India.
Sweta YadavGovernment Medical College, Kota, Rajasthan, India.
Kareena VaniaSmt. NHL Medical Municipal College, Ellisbridge, Ahmedabad, Gujarat, India.
Ashka PriyadarshiSmt. NHL Medical Municipal College, Ellisbridge, Ahmedabad, Gujarat, India.
Saakshi IjantkarDanylo Halytsky Lviv National Medical University, Ahmedabad, Gujarat, India.
Jana KotaichMedica Research Investigation, Hadath, Lebanon.ORCID https://orcid.org/0000-0002-7740-392X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic inflammation is the key pathophysiological link between psychological disorders and cardio-oncology, two seemingly separate clinical domains with increasingly acknowledged interdependencies. The inflammatory cascade not only plays a role in the etiology and development of several psychological disorders but is also a common biological substrate for cardiovascular difficulties in cancer patients (cardio-oncology). Despite mounting evidence of this tripartite link, clinical practice still uses fragmented integrated approaches to treating these interrelated illnesses. The purpose of this review is to compile the most recent data regarding the inflammatory pathways that are common to psychological illnesses, oncological processes, and cardiovascular side effects of cancer treatment. We examine how psychological discomfort in cancer patients worsens cardiovascular outcomes and how cardiovascular problems affect psychological well-being oppositely. Additionally, we assess new inflammatory biomarkers that may be useful for both diagnosis and prognosis in these disorders. This review offers a thorough framework for clinicians and researchers to address the intricate relationships between cancer treatment, psychological functioning, and cardiovascular health. It does so by looking at the most recent developments in anti-inflammatory interventions, pain management techniques, and integrated therapeutic approaches. Our goal is to draw attention to potential targeted therapies that use inflammatory pathway regulation to address several facets of this clinical triad at once.

Indexed as

cardio-oncologycardiotoxicitychronic inflammationinflammatory biomarkerspain managementpsychological disorders

Identifiers

PMID40851964
PMCPMC12369727

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.