ArticleAnnals of medicine and surgery (2012)2025
Bradycardia and hypotension associated with trigeminocardiac reflex during orthognathic surgery: two case reports.
Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A Call for Vigilance: Trigeminocardiac Reflex Presenting As Ventricular Bigeminy During Marginal Mandibulectomy.Cureus · 2026Article
- Ventricular Asystole During Le Fort I Orthognathic Surgery: A Case Consistent with Trigeminocardiac Reflex and a Mini Review.Clinics and practice · 2026Article
- Article
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Authors and funding
6 authors.
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Abstract
Introduction and importance: The trigeminocardiac reflex (TCR) is an uncommon but significant complication that can arise during orthognathic surgery. Case Presentation: We present two cases of TCR-induced bradycardia and hypotension during such procedures. In the first case, bradycardia was noted following a controlled downward fracture of the maxilla. In the second case, both bradycardia and hypotension occurred while the left mandibular ramus was split with a separator. Clinical Discussion: In both instances, interruption of the surgical procedure led to normalization of heart rate and blood pressure, indicating that TCR was likely triggered by stimulation of the second and third branches of the trigeminal nerve. Moreover, to the best of our knowledge, this is the first reported case of TCR during Le Fort I osteotomy in Japan. Conclusion: Given that TCR can potentially lead to cardiac arrest, surgeons must anticipate this reflex and communicate closely with the anesthesiologist to ensure prompt management.
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