Evidence map›Paper›PMID 40851938›Full record

ReviewAnnals of medicine and surgery (2012)2025

Artificial intelligence in disease diagnostics: a comprehensive narrative review of current advances, applications, and future challenges in healthcare.

Mohamed Baklola, Reem Reda Elmahdi, Shaimaa Ali, Mohamed Elshenawy, Ali Mohamed Mossad, Naji Al-Bawah, Rahma Mohamed Mansour

Registry-linked trialAbstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07333560 (Development and Pre-validated Multiple Variable Prediction Model Using Machine Learning for Early Functional Recovery After Joint Replacement Surgery.), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07333560 recruitingnot on this mapstarted 2026, after this paper: background citation

Development and Pre-validated Multiple Variable Prediction Model Using Machine Learning for Early Functional Recovery After Joint Replacement Surgery.

TypeobservationalSponsorIstituto Ortopedico RizzoliRan2026 to 2027Enrolled943ConditionsArtificial Intelligence (AI), Machine Learning, Joint Replacement, Predictive ModelArmsPredictive Model for Early Mobility Recovery and Length of Stay
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohamed BaklolaFaculty of Medicine, Mansoura University, Mansoura, Egypt.
Reem Reda ElmahdiFaculty of Medicine, Mansoura University, Mansoura, Egypt.
Shaimaa AliFaculty of Medicine, Mansoura University, Mansoura, Egypt.
Mohamed ElshenawyFaculty of Medicine, Mansoura University, Mansoura, Egypt.
Ali Mohamed MossadFaculty of Medicine, Mansoura University, Mansoura, Egypt.
Naji Al-BawahFaculty of Medicine, Sana'a University, Sana'a, Yemen.ORCID https://orcid.org/0009-0001-3519-6985
Rahma Mohamed MansourFaculty of Medicine, Mansoura University, Mansoura, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Artificial intelligence (AI) is revolutionizing healthcare, particularly in disease diagnostics, by improving accuracy, efficiency, and personalization. Its applications span medical imaging, pathology, and personalized medicine, significantly enhancing patient outcomes. However, challenges such as ethical dilemmas, data privacy concerns, and algorithmic biases hinder its full integration into clinical practice. A critical gap in the literature is the lack of comprehensive frameworks for addressing these challenges, particularly in low-resource settings. Aim: We aim to explore the current advancements, applications, and challenges of AI in disease diagnostics, emphasizing its transformative impact on healthcare systems. Materials and methods: A narrative review was conducted to explore the role of AI in disease diagnostics and healthcare. Results: AI has shown remarkable success in various domains such as medical imaging, pathology, and personalized medicine. Key technologies include machine learning, deep learning, and natural language processing, which have improved diagnostic accuracy and efficiency. Applications such as cancer detection, drug development, and wearable health monitoring devices have demonstrated a significant impact. However, challenges persist, including ethical dilemmas, algorithmic bias, regulatory gaps, and data security concerns. Innovative solutions like interdisciplinary collaboration, synthetic data generation, and robust legal frameworks are recommended to address these issues. Conclusion: AI's integration into disease diagnostics has the potential to revolutionize healthcare by improving outcomes and efficiency. Nonetheless, overcoming ethical, technical, and societal challenges is critical for realizing its full potential. Continued advancements in AI, combined with responsible implementation, can transform healthcare systems and pave the way for more equitable and effective medical practices.

Indexed as

artificial intelligencedeep learningdisease diagnosismachine learningpersonalized treatment

Identifiers

PMID40851938
PMCPMC12369792

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.