Evidence map›Paper›PMID 40851693›Full record

ArticleCureus2025

Hairy Cell Leukemia Diagnosed by Flow Cytometry Despite Absence of Hairy Cells in Peripheral Blood: A Case Report.

Kotaro Nakano, Yusuke Fukatsu, Shinichiro Oka, Takumi Takahashi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kotaro NakanoHematology, Iwata City Hospital, Iwata, JPN.
Yusuke FukatsuHematology, Iwata City Hospital, Iwata, JPN.
Shinichiro OkaHematology, Iwata City Hospital, Iwata, JPN.
Takumi TakahashiHematology, Iwata City Hospital, Iwata, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hairy cell leukemia (HCL) is a rare disease, and detecting hairy cells in peripheral blood is an essential initial step in its diagnosis. Flow cytometry (FCM) is a convenient and effective tool for assessing the immunophenotype, even without distinctive morphological features. We describe a case of HCL; primary myelofibrosis was initially suspected, but FCM findings ultimately led to the diagnosis of HCL. A 47-year-old male patient was admitted to the hospital with progression of pancytopenia, and splenomegaly was noted. The initial pathology report on bone marrow biopsy noted only MF-1 fibrosis. FCM examination showed positivity for CD19, CD20, CD11c, and CD25, and light-chain restriction. Bone marrow biopsy images showed fried egg-like cells, and

Indexed as

flow cytometeryhairy cell leukemia (hcl)myelofibrosispancytopeniaperipheral blood smearsplenomegaly

Identifiers

PMID40851693
PMCPMC12370212

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.