Evidence map›Paper›PMID 40851554›Full record

ArticleVeterinary clinical pathology2025

Hematology, Clinical Biochemistry, and Blood Cell Morphology Features of Captive Bothrops jararaca From Southeast Brazil.

Amanda O Alcantara, Bianca M M Reis, Juliana G Fonseca, Maíra A C Sousa, Vitor Hugo A Roxo, Guilherme J Souza, Fúlvia de Fátima A Castro, Guilherme N Souza, Jorlan Fernandes, Elba Regina S Lemos and 1 more

Abstract read
In one paragraph

Article in Veterinary clinical pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amanda O AlcantaraFaculdade de Veterinária, Universidade Federal Fluminense, Niterói, Brazil.ORCID https://orcid.org/0000-0002-7024-7602
Bianca M M ReisInstituto Vital Brazil, Niterói, Brazil.
Juliana G FonsecaInstituto Vital Brazil, Niterói, Brazil.
Maíra A C SousaFaculdade de Veterinária, Universidade Federal Fluminense, Niterói, Brazil.
Vitor Hugo A RoxoInstituto Vital Brazil, Niterói, Brazil.
Guilherme J SouzaInstituto Vital Brazil, Niterói, Brazil.
Fúlvia de Fátima A CastroDepartamento de Medicina Veterinária, Universidade Federal de Juiz de Fora, Juiz de Fora, Brazil.
Guilherme N SouzaDepartamento de Medicina Veterinária, Universidade Federal de Juiz de Fora, Juiz de Fora, Brazil.
Jorlan FernandesLaboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz/FIOCRUZ, Rio de Janeiro, Brazil.
Elba Regina S LemosLaboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz/FIOCRUZ, Rio de Janeiro, Brazil.
Aline M SouzaFaculdade de Veterinária, Universidade Federal Fluminense, Niterói, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 304282/2022-7Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/20-3.997/2024
6 · The paper itself

Abstract

backgroundSnakebite envenomation is a worldwide public health issue, particularly relevant to low and middle-income countries. Bothrops spp. antivenom is needed for snakebite treatment, which requires the maintenance of healthy snakes in captivity. Hematology and clinical biochemistry are important tools for monitoring the health status of these animals, as well as detecting hemoparasites (i.e., Hepatozoon spp.).

objectivesThis study aims to establish hematologic and biochemical reference intervals in a population of captive B. jararaca in a Brazilian serpentarium and assess blood cell morphology.

methodsBlood samples of 32 specimens of captive B. jararaca were collected and analyzed for complete blood count and biochemical variables, such as total proteins, albumin, cholesterol, triglycerides, calcium, phosphorus, urea, creatinine, uric acid, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl transferase, and creatine kinase. Blood smears were also evaluated to investigate blood parasites. Each variable was statistically analyzed according to the ASVCP guidelines and compared between sexes and the occurrence of Hepatozoon spp.

resultsThis study establishes the hematology and clinical biochemistry reference intervals and describes B. jararaca blood cell morphology. We observed no differences between sexes.

conclusionsOur study provides the first reference intervals for hematologic and biochemical variables for B. jararaca on the basis of ASCVP recommendations. The RI described could be essential for the management and treatment of B. jararaca kept under similar captive conditions.

Indexed as

Blood CellsBothropsAnimalsAnimals, ZooBlood Cell CountBlood Chemical AnalysisBothrops jararacaBrazilFemaleHematologic TestsMaleReference Valuesblood cell countclinical chemistryhemoparasiteHepatozoonsnakeViperidae

Identifiers

PMID40851554
PMCPMC12444004

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.