Evidence map›Paper›PMID 40851530›Full record

SynthesisThe neuroradiology journal2026

Comparing efficacy and safety of direct aspiration versus stent retriever thrombectomy in acute basilar artery occlusion: A systematic review and meta-analysis.

Muhammad Hassan Waseem, Zain Ul Abideen, Kanza Farhan, Haseeb Javed Khan, Dua Ghori, Misha Ahmed, Muhammad Burhan Tariq, Sania Aimen, Muhammad Wajih Ansari, Rowaid Ahmad and 1 more

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in The neuroradiology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Efficacy and Safety of Intravenous Thrombolytics in Ischemic Stroke Beyond the 4.5-Hour Time Window: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Muhammad Hassan WaseemNeurosurgery Department, Allama Iqbal Medical College, Pakistan.
Zain Ul AbideenNeurosurgery Department, King Edward Medical University, Pakistan.ORCID 0009-0001-8990-7738
Kanza FarhanNeurology Department, Jinnah Sindh Medical University, Pakistan.
Haseeb Javed KhanNeurosurgery Department, King Edward Medical University, Pakistan.
Dua GhoriNeurology Department, Dow Medical College, Pakistan.
Misha AhmedNeurology Department, Dow Medical College, Pakistan.
Muhammad Burhan TariqNeurology Department, Jinnah Sindh Medical University, Pakistan.
Sania AimenNeurology Department, Quetta Institute of Medical Sciences, Pakistan.
Muhammad Wajih AnsariNeurology Department, University of Texas Medical Branch, USA.
Rowaid AhmadNeurology Department, University of Texas Medical Branch, USA.
Zara FahimNeurosurgery Department, King Edward Medical University, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute basilar artery occlusion (BAO) can lead to severe stroke and is linked to significant disability or death if not treated. This meta-analysis evaluated the effectiveness and safety of first-line thrombectomy options: Direct Aspiration (DA) and Stent Retriever Thrombectomy (SRT) for acute BAO. Electronic databases, including PubMed, Cochrane Central, ScienceDirect, Embase, and Web of Science were searched from inception until July 2025. Studies were included if they were RCTs or observational cohorts involving adults with acute BAO, comparing DA and SRT. The risk ratios (RR) and mean differences (MD) were pooled using Review Manager version. The Newcastle-Ottawa Scale (NOS) was used to assess quality. This meta-analysis included fifteen observational studies pooling 2214 patients. DA significantly increased the postoperative successful (RR = 1.04; 95% CI: 1.01 to 1.07;

Indexed as

Arterial Occlusive DiseasesStentsThrombectomyVertebrobasilar InsufficiencyHumansSuctionTreatment Outcomeacute basilar artery occlusionDirect aspirationmechanical thrombectomymeta-analysisstent retriever

Identifiers

PMID40851530
PMCPMC12378274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.