Evidence map›Paper›PMID 40851516›Full record

ArticleProtein & cell2026

Structural basis of allosteric and bitopic ligands binding in sphingosine-1-phosphate receptors 2 and 3.

Yanhong Wu, Qiuru Chen, Hongyu Wang, Kezhen Liu, Jiaxin Wei, Mu Wang, Kun Chen, Ya Zhu, Shuo Han, Cuiying Yi and 9 more

Abstract read
In one paragraph

Article in Protein & cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yanhong WuState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Qiuru ChenState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Hongyu WangState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Kezhen LiuState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Jiaxin WeiState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Mu WangState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Kun ChenState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Ya ZhuLingang Laboratory, Shanghai 200031, China.
Shuo HanState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Cuiying YiState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Limin MaState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Gisela SchnappBoehringer-Ingelheim Pharma GmbH & Co. KG, Department of Medicinal Chemistry, Biberach 88397, Germany.
Alexander PautschBoehringer-Ingelheim Pharma GmbH & Co. KG, Department of Medicinal Chemistry, Biberach 88397, Germany.
Christian GnammBoehringer-Ingelheim Pharma GmbH & Co. KG, Department of Medicinal Chemistry, Biberach 88397, Germany.
Matthias GrauertBoehringer-Ingelheim Pharma GmbH & Co. KG, Department of Medicinal Chemistry, Biberach 88397, Germany.
Esther SchmidtBoehringer-Ingelheim Pharma GmbH & Co. KG, Department of Drug Discovery Sciences, Biberach 88397, Germany.
Qiuxiang TanState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Beili WuState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Qiang ZhaoState Key Laboratory of Drug Research and State Key Laboratory of Chemistry Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40851516
PMCPMC13340923

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.