Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
9 authors.
Jixing LyuDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Hanieh BahramimoghaddamDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Tianqi ZhangDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Elena ScottDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Sangho D YunDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Gaya P YadavLaboratory for Biomolecular Structure and Dynamics (LBSD), Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843, United States.
Minglei ZhaoDepartment of Biochemistry and Molecular biology, University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0001-5832-6060
David RussellDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Arthur LaganowskyDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0001-5012-5547
Funding
Understanding the role of lipids in structure and function of membrane proteinsRM1GM145416 · NIGMS · TEXAS A&M UNIVERSITY · PI Erin S Baker, Arthur D Laganowsky · 2022 to 2026
$7.4M
Native Mass Spectrometry Guided Structural Biology CenterRM1GM149374 · NIGMS · OHIO STATE UNIVERSITY · PI Vicki H. Wysocki · 2023 to 2026
$5.0M
Structural and Functional Studies of Molecular Machines Involved in Chemical Modifications of MacromoleculesR35GM143052 · NIGMS · UNIVERSITY OF CHICAGO · PI ZHAO, MINGLEI · 2021 to 2025
$2.1M
Innovative Native Ion Mobility Approaches for Transformational Measurements in Structural BiologyR01GM138863 · NIGMS · TEXAS A&M UNIVERSITY · PI CLOWERS, BRIAN, LAGANOWSKY, ARTHUR D · 2020 to 2023
$1.2M
Developing new tools to probe membrane protein-lipid interactions for biomedical applicationsR01GM139876 · NIGMS · TEXAS A&M UNIVERSITY · PI LAGANOWSKY, ARTHUR D · 2021 to 2024
Proteins involved in the biogenesis of lipopolysaccharide (LPS), a lipid exclusive to Gram-negative bacteria, are promising candidates for drug discovery. Specifically, the ABC transporter MsbA plays a crucial role in translocating an LPS precursor from the cytoplasmic to the periplasmic facing leaflet of the inner membrane, and small molecules that inhibit its function exhibit bactericidal activity. Here, we use native mass spectrometry (MS) to determine lipid binding affinities of MsbA from
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Molecular Basis for the Activation of · full record | OpenQuestion