Evidence map›Paper›PMID 40851283›Full record

ArticleUltrastructural pathology2025

The dimorphism of the multinucleated giant cells of gliomas.

Muhi Dean Barazi, John Paul Aboubechara, Muhammad Sulman, Haitham H Maraqah, Mones S Abu-Asab, Han Sung Lee, Orwa Aboud

Abstract read
In one paragraph

Article in Ultrastructural pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muhi Dean BaraziSchool of Biosciences, Rice University, Houston, TX, USA.ORCID 0009-0007-7605-7715
John Paul AboubecharaDepartment of Neurology and Neurosurgery, UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, CA, USA.ORCID 0000-0002-9363-5704
Muhammad SulmanDepartment of Neurology and Neurosurgery, UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, CA, USA.
Haitham H MaraqahMedicine & Health Science Faculty, School of Medicine, An-Najah National University, Nablus, Palestine.ORCID 0000-0002-2827-6573
Mones S Abu-AsabPhyloncology, LLC, Bethesda, MD, USA.ORCID 0000-0002-4047-1232
Han Sung LeeDepartment of Pathology and Laboratory Medicine, UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, CA, USA.
Orwa AboudDepartment of Neurology and Neurosurgery, UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, CA, USA.ORCID 0000-0002-7916-1629

Funding

UC Davis Paul Calabresi K12 Clinical Oncology Research Career Development ProgramK12CA138464 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BIRKELAND, ANDREW CHARLES, LARA, PRIMO N. · 2011 to 2025
$11.4M
NCI NIH HHS K12 CA138464
6 · The paper itself

Abstract

Extensive research has begun to uncover the molecular characteristics of high grade gliomas. However, an ultrastructural understanding of their pathogenesis remains largely unexplored. Multinucleated giant cells are large cells with multiple nuclei thought to form from the fusion of multiple neoplastic cells. In this study, we aim to elucidate the nature of the multinucleated giant cells (MGCs) within

Indexed as

AstrocytomaBrain NeoplasmsGiant CellsGlioblastomaGliomaAdultAgedFemaleHumansMaleMicroscopy, Electron, TransmissionMiddle AgedMutationAstrocytomaelectron microscopygiant cellglioblastoma multiformeIDH1-mtintermediate filamentsmultinucleated giant cellstumor mobility

Identifiers

PMID40851283
PMCPMC12456927

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.