Evidence map›Paper›PMID 40851213›Full record

ArticleEndocrine, metabolic & immune disorders drug targets2026

Continuous Interstitial Glucose Monitoring through a Long-Term Subcutaneous Implantable Sensor during Pregnancy in Type 1 Diabetes: A Two- Patient Case Report.

Betella Nazarena, Resi Veronica, Gaglio Alessia, Ciafardini Antea, Mazzoleni Federica, Vena Walter, Orsi Emanuela, Bossi Antonio Carlo

Abstract readCase Reports
In one paragraph

Article in Endocrine, metabolic & immune disorders drug targets, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Betella NazarenaEndocrinology and Diabetology Unit, Humanitas Gavazzeni Institute, via M. Gavazzeni 21, 24100, Bergamo, Italy.ORCID 0000-0002-1791-789X
Resi VeronicaEndocrinology and Metabolic Diseases Unit, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy.ORCID 0000-0002-8443-7773
Gaglio AlessiaEndocrinology and Metabolic Diseases Unit, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy.ORCID 0000-0001-6414-9558
Ciafardini AnteaEndocrinology and Diabetology Unit, Humanitas Gavazzeni Institute, via M. Gavazzeni 21, 24100, Bergamo, Italy.ORCID 0009-0006-3832-8169
Mazzoleni FedericaEndocrinology and Diabetology Unit, Humanitas Gavazzeni Institute, via M. Gavazzeni 21, 24100, Bergamo, Italy.ORCID 0009-0001-9895-8916
Vena WalterEndocrinology and Diabetology Unit, Humanitas Gavazzeni Institute, via M. Gavazzeni 21, 24100, Bergamo, Italy.ORCID 0000-0002-9288-6261
Orsi EmanuelaEndocrinology and Metabolic Diseases Unit, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy.ORCID 0000-0002-1255-8437
Bossi Antonio CarloEndocrinology and Diabetology Unit, Humanitas Gavazzeni Institute, via M. Gavazzeni 21, 24100, Bergamo, Italy.ORCID 0000-0001-8900-1787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOptimal glycaemic control is crucial during pregnancy in women with type 1 diabetes mellitus (T1D). Current guidelines, based on positive data from the CONCEPTT (Continuous Glucose Monitoring in Pregnant Women With Type 1 Diabetes Trial), on maternal glycaemic control and fetal outcomes, recommend offering real-time Continuous Glucose Monitoring (rt-CGM) as a standard method in all pregnancies of women with type 1 diabetes (T1D). CASE PRESENTATION: In these two clinical cases, we describe for the first time the gestational outcomes in two patients with T1D who chose to maintain a long-term implantable subcutaneous sensor (Eversense XL®) as a CGM method during their pregnancies. The first case concerns a 33- year-old young woman with a 25-year history of T1D on Continuous Subcutaneous Insulin Infusion (CSII), who faced her first pregnancy with a suboptimal preconception glycaemic control; the second case describes the second pregnancy of a 37-year-old patient with a more recently diagnosed T1D, on multiple daily injection (MDI) therapy who achieved adequate glycaemic compensation before planned conception.

conclusionThe subcutaneous sensor replacement was carried out at the beginning and end of the 2

Indexed as

Blood GlucoseBlood Glucose Self-MonitoringContinuous Glucose MonitoringDiabetes Mellitus, Type 1Insulin Infusion SystemsPregnancy in DiabeticsAdultFemaleGlycemic ControlHumansHypoglycemic AgentsInsulinPregnancyBlood GlucoseHypoglycemic AgentsInsulingestational outcomesglucose monitoringinsulin dosepregnancysubcutaneous implantable sensorType 1 diabetes

Identifiers

PMID40851213
PMCPMC13662724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.