Evidence map›Paper›PMID 40851212›Full record

ReviewRecent advances in drug delivery and formulation2026

Nanorobots: Trailblazing the Future of Pharmaceuticals Through Targeted Therapy and Disease Monitoring.

P Sree Ranjani, S Sangeetha, K K Suriya Prakaash, N Damodharan

Abstract readReview
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In one paragraph

Review in Recent advances in drug delivery and formulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

P Sree RanjaniDepartment of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India.ORCID 0009-0002-3521-6699
S SangeethaDepartment of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India.
K K Suriya PrakaashDepartment of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India.ORCID 0009-0006-9479-2935
N DamodharanDepartment of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis review explores the design principles, sensor mechanisms, and propulsion systems of nanorobots, highlighting their applications in targeted drug delivery, disease monitoring, and broader biomedical fields. The objective is to provide a comprehensive overview of how nanorobots transform pharmaceutical delivery systems and precision therapy.

methodsA structured literature search was conducted using electronic databases, including Pub- Med, Scopus, and Web of Science. Keywords such as Nanorobots, Nanorobot propulsion, Biosensors, Magnetically driven nanorobots, Electric field-driven nanorobots, Biomedical applications, and Enzyme-driven nanorobots were used. Articles published between 2010 and 2024 were considered. Inclusion criteria involved peer-reviewed articles focusing on nanorobot design, propulsion systems, sensor mechanisms, and clinical applications. Non-English articles and non-peer-reviewed content were excluded.

resultsA total of 212 relevant studies were initially identified through a comprehensive search across PubMed, Scopus, Web of Science, and Google Scholar. After applying inclusion and exclusion criteria, 94 studies were selected for final analysis, focusing on the integration of sensors, propulsion systems, and energy sources in nanorobots. DISCUSSION: The review revealed that nanorobots utilize advanced sensor systems (nanocantilevers and biosensors) for molecular recognition and site-specific targeting. These sensors detect biochemical and mechanical changes, aiding precise navigation. Powered by external forces (magnetic, electric, light, ultrasound) or internal biochemical energy (enzymatic or chemical reactions), propulsion mechanisms enable controlled movement and drug delivery. Nanorobots constructed from silicon, polymers, and piezoelectric compounds exhibit functional adaptability. Their applications span targeted drug delivery, oncology, neurosurgery, vascular medicine, and environmental remediation.

conclusionNanorobots represent a trailblazing pharmaceutical innovation, offering highly specific, efficient, and minimally invasive drug delivery and disease monitoring capabilities. Their combination of biosensing and propulsion mechanisms enhances targeted delivery and clinical efficacy. Continued development in nanorobotic systems holds the potential to revolutionize clinical treatments and improve patient outcomes across multiple therapeutic domains.

Indexed as

Drug Delivery SystemsRoboticsAnimalsBiosensing TechniquesHumansNanotechnologybiosensing techniqueselectrical stimulation therapymagnetic fieldsmicroelectromechanical devicesnanorobotsNanotechnologyphototherapy

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.