Evidence map›Paper›PMID 40850743›Full record

ArticleJournal of clinical pathology2026

Shortwave infrared imaging increases the number of lymph nodes and improves cancer staging: a 104-patient study.

Julie M Jorns, Randall S Smith, Dennis Strenk, Greg Stauble, Sihem Khelifa, Ryan Seltzer, John Manuel, Matthew W Rosenbaum, James Almas, Zhongming Li

Abstract read
In one paragraph

Article in Journal of clinical pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Julie M JornsPathology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.ORCID http://orcid.org/0000-0002-7777-6670
Randall S SmithSt Dominic Memorial Hospital, Jackson, Mississippi, USA.
Dennis StrenkWisconsin Diagnostic Laboratories LLC, Milwaukee, Wisconsin, USA.
Greg StaubleSt Dominic Memorial Hospital, Jackson, Mississippi, USA.
Sihem KhelifaCision Vision Inc, Mountain View, California, USA.
Ryan SeltzerCision Vision Inc, Mountain View, California, USA.
John ManuelCision Vision Inc, Mountain View, California, USA.
Matthew W RosenbaumCision Vision Inc, Mountain View, California, USA.
James AlmasCision Vision Inc, Mountain View, California, USA.
Zhongming LiCision Vision Inc, Mountain View, California, USA jeremy@cisionvision.com.ORCID http://orcid.org/0009-0006-9984-305X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsAdequate lymph node examination is key to accurate cancer staging. This study investigates the effectiveness of shortwave infrared imaging in increasing the overall and positive lymph node numbers.

methodsSpecimens from various anatomic sites, including colorectal, pancreatic, breast, gastric, skin and small bowel resections, were evaluated. 104 specimens were first grossed with manual palpation and then grossed with the assistance of shortwave infrared imaging. The overall and positive lymph node numbers were documented.

resultsIn 90 of the 104 cases (86.5%), shortwave infrared imaging helped identify additional lymph nodes. On average, 4.81 additional lymph nodes were found. In 11 of the 104 cases (10.6%), additional positive lymph nodes were found. In 4 of the 104 cases (3.8%), cancer stages were changed.

conclusionsShortwave infrared imaging may increase the number of lymph nodes identified and has the potential to improve cancer staging accuracy. Further validation in larger, randomised or prospective studies is warranted.

Indexed as

Infrared RaysLymphatic MetastasisLymph NodesNeoplasmsNeoplasm StagingAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedColorectal NeoplasmsHead and Neck NeoplasmsLYMPH NODESMedical Oncology

Identifiers

PMID40850743
PMCPMC12911634

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.