Evidence map›Paper›PMID 40850152›Full record

ArticlePhysical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine2025

Biopsychosocial profiles following ACL reconstruction: A latent class analysis of barriers to return-to-activity.

Erich Petushek, Matthew S Harkey, Kim Santiago, Alexander Stamm, Shelby Baez, Jed A Diekfuss, Gregory D Myer, Christopher Kuenze

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Erich PetushekDepartment of Psychology and Human Factors, Michigan Technological University, MI, USA; Health Research Institute, Michigan Technological University, MI, USA; College of Human Medicine, Michigan State University, MI, USA. Electronic address: ejpetush@mtu.edu.
Matthew S HarkeyDepartment of Kinesiology, Michigan State University, MI, USA.
Kim SantiagoCollege of Human Medicine, Michigan State University, MI, USA.
Alexander StammCollege of Human Medicine, Michigan State University, MI, USA.
Shelby BaezDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jed A DiekfussEmory Sports Performance and Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA.
Gregory D MyerEmory Sports Performance and Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Atlanta, GA, USA.
Christopher KuenzeDepartment of Kinesiology, University of Virginia, Charlottesville, VA, USA.

Funding

Multi-site Randomized Clinical Trial of FIT Teens for Juvenile FibromyalgiaR01AR070474 · NIAMS · CINCINNATI CHILDRENS HOSP MED CTR · PI KASHIKAR-ZUCK, SUSMITA · 2017 to 2023
$8.7M
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female AthletesR01AR055563 · NIAMS · OHIO STATE UNIVERSITY · PI BATES, NATHANIEL ANDREW, KRYCH, AARON · 2008 to 2022
$5.9M
Real-Time Sensorimotor Feedback for Injury Prevention Assessed in Virtual RealityU01AR067997 · NIAMS · EMORY UNIVERSITY · PI MYER, GREGORY DONALD · 2016 to 2022
$3.6M
Integrative Training Program for Pediatric Sickle Cell PainR61AT012421 · NCCIH · EMORY UNIVERSITY · PI SIL, SOUMITRI · 2022 to 2022
$1.3M
Neuroplastic Mechanisms for Acquisition and Transfer of Injury-Resistant Movement Patterns Assessed in VR Simulated SportR01AR076153 · NIAMS · EMORY UNIVERSITY · PI GROOMS, DUSTIN ROBERT, MYER, GREGORY DONALD · 2020 to 2022
$1.1M
Walk this Way: Physical Activity and Walking Biomechanics Lead to Early Knee OA Symptoms and Ultrasound-Detected Structural Pathology after ACL ReconstructionK01AR081389 · NIAMS · MICHIGAN STATE UNIVERSITY · PI Matthew Harkey · 2022 to 2026
$689k
Discovery of the Neural Drivers Underlying Injury-Risk BiomechanicsR01AR077248 · NIAMS · OHIO UNIVERSITY ATHENS · PI GROOMS, DUSTIN ROBERT · 2021 to 2023
$557k
NCCIH NIH HHS R61 AT012421NIAMS NIH HHS K01 AR081389NIAMS NIH HHS L30 AR076101NIAMS NIH HHS R01 AR055563NIAMS NIH HHS R01 AR070474NIAMS NIH HHS R01 AR076153NIAMS NIH HHS R01 AR077248NIAMS NIH HHS U01 AR067997
6 · The paper itself

Abstract

objectiveUnderstanding of how biopsychosocial factors interrelate to affect recovery from ACL injuries is essential for improving patient outcomes. This research aimed to use Latent Class Analysis (LCA) to classify individuals post-ACL reconstruction into subgroups reflecting their particular biopsychosocial challenges to recovery.

designCross-Sectional.

methodsThis multisite investigation included 134 ACLR patients approximately 6 months (5.6 months ± 1.8 SD) following surgery. The ACL Reasons scale, various Patient Reported Outcome (PRO), and performance-based measures were assessed. LCA was used to categorize patients into subgroups based on the ACL Reasons scale. Subgroups were then compared across demographic, PRO, and performance-based measures using one-way analysis of variance and chi-squared tests.

resultsLCA identified two distinct groups of patients who were less active after ACL reconstruction, characterized by varying levels of injury related fear, anxiety and depression. These groups reported lower outcomes and demonstrated reduced performance on hop tests in comparison to those who were as active as before their surgery.

conclusionPatients less active post-surgery fall into two categories: one hindered by injury-related fear and symptoms, the other by mostly symptoms alone. Tailored interventions could enhance recovery, with one group possibly benefiting from psychological support and the other from a focus on functional and symptomatic treatment.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionReturn to SportAdolescentAdultAnxietyCross-Sectional StudiesDepressionFearFemaleHumansLatent Class AnalysisMalePatient Reported Outcome MeasuresRecovery of FunctionYoung AdultInjury-related fearModel-based clusteringPatient subgroupingReadinessRehabilitation outcomes

Identifiers

PMID40850152
PMCPMC12710663

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.