Evidence map›Paper›PMID 40849925›Full record

ArticleOncology nursing forum2025

Physical Function and Mobility in Older Adults Receiving Treatment for Acute Myeloid Leukemia: A Longitudinal Qualitative Study.

Ahrang Jung, Victoria Crowder, Ya-Ning Chan, Dawn Klemm, Kelly R Tan, Elissa Herman Poor, Ayomide Okanlawon Bankole, Danielle Steele Anderson, Susan Coppola, Mackenzi Pergolotti and 3 more

Abstract read
In one paragraph

Article in Oncology nursing forum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ahrang JungAhrang Jung.
Victoria CrowderVictoria Crowder.
Ya-Ning ChanYa-Ning Chan.
Dawn KlemmDawn Klemm.
Kelly R TanKelly R. Tan.
Elissa Herman PoorElissa Herman Poor.
Ayomide Okanlawon BankoleAyomide Okanlawon Bankole.
Danielle Steele AndersonDanielle Steele Anderson.
Susan CoppolaSusan Coppola.
Mackenzi PergolottiMackenzi Pergolotti.
Todd A SchwartzTodd A. Schwartz.
Daniel R RichardsonDaniel R. Richardson.
Ashley Leak BryantAshley Leak Bryant.

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5M
INTERVENTIONS FOR PREVENTING &MANAGING CHRONIC ILLNESST32NR007091 · NINR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Cheryl L Giscombe, Cathi Barbra Propper · 1996 to 2026
$11.8M
A Nurse-Led Palliative and Supportive Care Intervention for Newly Diagnosed Adults with Acute Myeloid LeukemiaR34NR019131 · NINR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRYANT, ASHLEY LEAK · 2021 to 2022
$389k
NCI NIH HHS P30 CA016086NINR NIH HHS R34 NR019131NINR NIH HHS T32 NR007091
6 · The paper itself

Abstract

purposeTo explore perspectives of older adults (aged 60 years or older) with acute myeloid leukemia (AML) on their physical function and mobility, assessed at three time points during treatment with a hypomethylating agent and venetoclax (HMA + VEN). PARTICIPANTS &

settingParticipants were older adults with AML (N = 17) receiving HMA + VEN at a comprehensive cancer center. Most were male and aged 64-89 years (median age = 75 years). METHODOLOGIC APPROACH: This study used a longitudinal qualitative approach with semistructured interviews at cycles 1, 2, and 7 of chemotherapy. Interviews were audio recorded, transcribed, coded, and analyzed using thematic analysis.

findingsFour themes were identified: reduced mobility and limited options for physical activities (cycle 1), periodic changes in mobility and energy level (cycle 2), acceptance and adaptation to changed mobility (cycle 7), and strategies to stay active. IMPLICATIONS FOR NURSING: Substantial challenges with physical function and mobility exist for older adults undergoing treatment for AML. Oncology nurses should anticipate patient needs, provide appropriate care, and make referrals to address physical and functional needs before and during HMA + VEN treatment.

Indexed as

Antineoplastic AgentsExerciseLeukemia, Myeloid, AcuteMobility LimitationAgedAged, 80 and overBridged Bicyclo Compounds, HeterocyclicFemaleHumansLongitudinal StudiesMaleMiddle AgedQualitative ResearchSulfonamidesAntineoplastic AgentsBridged Bicyclo Compounds, HeterocyclicSulfonamidesvenetoclaxacute myeloid leukemialow-intensity chemotherapymobilityphysical functioning

Identifiers

PMID40849925
PMCPMC12377868

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.