ReviewCurrent rheumatology reviews2026
The Bidirectional Relationship between Psoriatic Arthritis and Mental Health: A Comprehensive Review.
Review in Current rheumatology reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPsoriatic arthritis (PsA) is a long-standing inflammatory immune-mediated condition that involves articular and peri-articular tissues and frequently accompanies psoriasis (PsO). It is defined by chronic joint inflammation, pain, and structural damage, resulting in impairment of physical function and quality of life. Increasing evidence points to the close relationship between PsA and mental disorders, especially depression and anxiety.
methodsThis review utilized an extensive literature search approach to select studies addressing the correlation between psoriatic arthritis (PsA) and mental comorbidities such as depression, anxiety, and their influence on quality of life and the disease course. Databases like PubMed, Scopus, Web of Science, and Google Scholar were utilized up to 2024 with applicable keywords and Boolean operators.
resultsThe mutual interaction between PsA and psychological distress is moderated by mechanisms including chronic pain, systemic inflammation, physical disability, and the social stigma of psoriatic lesions. Research suggests that patients with PsA exhibit an increased frequency of anxiety and depression in comparison to the general population, and that mental illness augments the severity of the disease and affects the outcome of treatments adversely. In addition, PsA may also cause systemic inflammation that might lead to neurocognitive dysfunction, adding to the risk for mood disorders. DISCUSSION: Although there is a long-standing, well-documented psychosocial morbidity associated with PsA, mental health comorbidities are frequently underdiagnosed and undertreated. Psychological distress must be treated as an integral part of PsA management to enhance patient-reported outcomes as well as quality of life.
conclusionThis review examines the complex interaction between PsA and mental health, considers the possible underlying mechanisms, and highlights the necessity of an integrated, multidisciplinary treatment strategy for patients.
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Identifiers
40849738What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.