ArticleAsian Pacific journal of cancer prevention : APJCP2025
Enhanced Antibacterial, Anti-Biofilm, and Anticancer Activities of Liposome-Encapsulated Selenium Nanoparticles: A Novel Therapeutic Approach.
Article in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Liposome drug delivery strategies: state-of-the-art for combating bacterial biofilms.Frontiers in microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study investigates the green synthesis of selenium nanoparticles (SeNPs) and their encapsulation in liposomes as a novel drug delivery system to enhance the antibacterial and anticancer properties of SeNPs. Liposomes are well-known for their ability to improve the biological activity of encapsulated drugs, making them a promising candidate for targeted therapies, particularly in oral cancer treatment.
methodsBiosynthesised SeNPs were incorporated into liposomes via the thin-film hydration technique. Particle size and zeta potential were quantified by dynamic light scattering (DLS), whereas encapsulation efficiency (EE) was determined spectrophotometrically (UV-Vis).
resultsThe physicochemical properties of the liposome-loaded SeNPs were characterized, revealing an average size of 270 nm, spherical morphology, and an encapsulation efficiency of 50.5%. The release profile of SeNPs from the liposomes demonstrated a controlled release of 61% over 64 hours, while free SeNPs released 100% of their content during the same period. The antibacterial and anti-biofilm activities of both free and liposome-loaded SeNPs were tested against standard pathogenic bacterial strains, with the liposome formulation showing enhanced efficacy. The cytotoxicity assay revealed that liposome-loaded SeNPs exhibited significantly higher cytotoxic effects on oral cells compared to free SeNPs, indicating improved therapeutic potential.
conclusionThe study demonstrates that liposome-loaded SeNPs are an effective and biocompatible drug delivery system with notable antibacterial, anti-biofilm, and anticancer properties, making them a promising candidate for targeted drug delivery in oral cancer therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.