Evidence map›Paper›PMID 40849448›Full record

ArticleBMC anesthesiology2025

Gas composition and pressure in the hypopharynx during high-flow oxygen therapy through a nasal cannula in healthy volunteers with different breathing patterns.

Andrey I Yaroshetskiy, Anna P Krasnoshchekova, Fedor D Tkachenko, Alina V Rubashchenko, Daniil D Zubarev, Vasiliy D Konanykhin, Maxim I Savelenok, Maxim M Nosenko, Zamira M Merzhoeva, Sergey N Avdeev

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06189716 (Evaluation of Gas Composition in the Oropharynx During High-flow Oxygen Therapy Through Nasal Cannula in Healthy Volunteers), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06189716 nacompletednot on this map

Evaluation of Gas Composition in the Oropharynx During High-flow Oxygen Therapy Through Nasal Cannula in Healthy Volunteers: a Physiological Study

TypeinterventionalSponsorI.M. Sechenov First Moscow State Medical UniversityRan2024 to 2024Enrolled20ConditionsHealthy VolunteersArmsHigh flow oxygen through nasal cannula
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrey I YaroshetskiyPulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str, Moscow, 119991, Russia. dr.intensivist@gmail.com.ORCID http://orcid.org/0000-0002-1484-092X
Anna P KrasnoshchekovaPulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str, Moscow, 119991, Russia.ORCID http://orcid.org/0000-0001-6986-1368
Fedor D TkachenkoPulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str, Moscow, 119991, Russia.ORCID http://orcid.org/0009-0009-6219-844X
Alina V RubashchenkoPulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str, Moscow, 119991, Russia.ORCID http://orcid.org/0009-0004-9505-5772
Daniil D ZubarevPulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str, Moscow, 119991, Russia.ORCID http://orcid.org/0009-0009-7425-746X
Vasiliy D KonanykhinPulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str, Moscow, 119991, Russia.ORCID http://orcid.org/0000-0002-6558-1227
Maxim I SavelenokPulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str, Moscow, 119991, Russia.ORCID http://orcid.org/0000-0003-0367-3756
Maxim M NosenkoPulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str, Moscow, 119991, Russia.ORCID http://orcid.org/0009-0009-5596-0328
Zamira M MerzhoevaPulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str, Moscow, 119991, Russia.ORCID http://orcid.org/0000-0002-3174-5000
Sergey N AvdeevPulmonology Department, Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str, Moscow, 119991, Russia.ORCID http://orcid.org/0000-0002-5999-2150

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-flow nasal cannula is widespread in patients with hypoxemic and hypercapnic respiratory failure, but physiological data concerning influence of the combination of breathing pattern, preset flow rate (PFR), and inspiratory oxygen fraction (F

methodsThe study included 20 healthy subjects with 12 combinations of PFR (30-60-80 L/min) and F

resultsInspiratory oxygen fraction (FiO

conclusionHCM, OM, and HOM in healthy subjects decreased FiO

trial registrationClinicalTrials.gov identifier: NCT06189716 , registered on 19/12/2023.

Indexed as

HypopharynxOxygen Inhalation TherapyRespirationAdultCannulaCarbon DioxideFemaleHealthy VolunteersHumansMaleOxygenTidal VolumeYoung AdultCarbon DioxideOxygenAirway pressureCapnographyHigh-flow nasal cannulaOximetryPhysiological effects

Identifiers

PMID40849448
PMCPMC12374479

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.