Evidence map›Paper›PMID 40849424›Full record

ArticleNature communications2025

Towards generalist foundation model for radiology by leveraging web-scale 2D&3D medical data.

Chaoyi Wu, Xiaoman Zhang, Ya Zhang, Hui Hui, Yanfeng Wang, Weidi Xie

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed.

  1. Article
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  9. Review
  10. Review
  11. Article
  12. Why Only 3D for 3D? 2D-Guided Supervision for 3D Medical Vision-Language Models.KDD : proceedings. International Conference on Knowledge Discovery & Data Mining · 2026
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. MARCH: Multi-Agent Radiology Clinical Hierarchy for CT Report Generation.Proceedings of the conference. Association for Computational Linguistics. Meeting · 2026
    Article
  18. Review
  19. Article
  20. Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chaoyi Wu *Shanghai Jiao Tong University, Shanghai, China.
Xiaoman Zhang *Shanghai Jiao Tong University, Shanghai, China.ORCID http://orcid.org/0000-0002-7696-9366
Ya ZhangShanghai Jiao Tong University, Shanghai, China.ORCID http://orcid.org/0000-0002-5390-9053
Hui HuiShanghai Jiao Tong University, Shanghai, China.
Yanfeng WangShanghai Jiao Tong University, Shanghai, China. wangyanfeng622@sjtu.edu.cn.ORCID http://orcid.org/0000-0002-3196-2347
Weidi XieShanghai Jiao Tong University, Shanghai, China. weidi@sjtu.edu.cn.ORCID http://orcid.org/0009-0002-8609-6826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, as a proof-of-concept, we aim to initiate the development of Radiology Foundation Model, termed as RadFM. We consider three perspectives: dataset construction, model design, and thorough evaluation, concluded as follows: (i), we contribute 4 multimodal datasets with 13M 2D images and 615K 3D scans. When combined with a vast collection of existing datasets, this forms our training dataset, termed as Medical Multi-modal Dataset, MedMD. (ii), we propose an architecture that enables to integrate text input with 2D or 3D medical scans, and generates responses for diverse radiologic tasks, including diagnosis, visual question answering, report generation, and rationale diagnosis; (iii), beyond evaluation on 9 existing datasets, we propose a new benchmark, RadBench, comprising three tasks aiming to assess foundation models comprehensively. We conduct both automatic and human evaluations on RadBench. RadFM outperforms former accessible multi-modal foundation models, including GPT-4V. Additionally, we adapt RadFM for diverse public benchmarks, surpassing various existing SOTAs.

Indexed as

Imaging, Three-DimensionalInternetRadiologyDatabases, FactualHumans

Identifiers

PMID40849424
PMCPMC12375113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.