Evidence map›Paper›PMID 40849362›Full record

ArticleAnnals of biomedical engineering2025

Accuracy and Reliability of Synthetic Computed Tomography for Model-Based Tracking of Biplane Videoradiography Data.

Seth J Kussow, Jared L Zitnay, Penny R Atkins, Andrew E Anderson

Abstract read
In one paragraph

Article in Annals of biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seth J KussowDepartment of Orthopaedics, University of Utah School of Medicine, 590 Wakara Way, Salt Lake City, UT, 84108, USA.
Jared L ZitnayDepartment of Orthopaedics, University of Utah School of Medicine, 590 Wakara Way, Salt Lake City, UT, 84108, USA.
Penny R AtkinsScientific Computing and Imaging Institute, University of Utah, 72 S Central Campus Dr., Salt Lake City, UT, 84112, USA.
Andrew E AndersonDepartment of Orthopaedics, University of Utah School of Medicine, 590 Wakara Way, Salt Lake City, UT, 84108, USA. andrew.anderson@hsc.utah.edu.ORCID http://orcid.org/0000-0003-4708-2608

Funding

TRD - VisualizationP41GM103545 · NIGMS · UNIVERSITY OF UTAH · PI JOHNSON, CHRISTOPHER R., MACLEOD, ROB S. · 2012 to 2019
$9.7M
Population-Based Shape and Biomechanical Analysis of Hip PathoanatomyR01EB016701 · NIBIB · UNIVERSITY OF UTAH · PI ANDERSON, ANDREW EDWARD · 2013 to 2023
$3.6M
ShapeWorks in the CloudR01AR076120 · NIAMS · UNIVERSITY OF UTAH · PI ELHABIAN, SHIREEN YOUSSEF · 2019 to 2024
$2.7M
Morphological and Biomechanical Insights into the Pathophysiology of Femoroacetabular Impingement SyndromeR01AR077636 · NIAMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI ANDERSON, ANDREW EDWARD · 2020 to 2025
$2.3M
New 3D and 4D Image-Based Clinical Measures of Atrial Structural and Functional Remodeling in Atrial FibrillationR01HL135568 · NHLBI · UNIVERSITY OF UTAH · PI CATES, JOSHUA E, ELHABIAN, SHIREEN YOUSSEF · 2017 to 2020
$1.4M
ShapeWorksStudio: An Integrative, User-Friendly, and Scalable Suite for Shape Representation and AnalysisU24EB029011 · NIBIB · UNIVERSITY OF UTAH · PI ELHABIAN, SHIREEN YOUSSEF · 2019 to 2023
$1.4M
NHLBI NIH HHS R01 HL135568NIAMS NIH HHS R01 AR076120NIAMS NIH HHS R01 AR077636NIAMS NIH HHS R01AR077636NIBIB NIH HHS R01 EB016701NIBIB NIH HHS U24 EB029011NIGMS NIH HHS P41 GM103545
6 · The paper itself

Abstract

purposeBiplane videoradiography (BVR) accurately measures hip kinematics in vivo. One downside of BVR is that it typically requires a pelvic computed tomography (CT) scan to reconstruct surfaces for model-based tracking (MBT), increasing the radiation burden to participants. Synthetic CT (sCT) from magnetic resonance imaging (MRI) provides similar volumetric image-based data. The purpose of this study was to assess the effect sCT has on the accuracy and reliability of in vivo hip kinematics from BVR data.

methodsThree asymptomatic participants received CT and MRI scans and were imaged with BVR while standing and during gait. Kinematics were calculated from femur and pelvis surfaces reconstructed from CT and sCT scans. Accuracy and inter-/intra-reviewer reliability of hip kinematics using sCT were assessed against CT as the reference using mean absolute error (MAE), mean difference (MD), precision, and inter-/intra-class correlation coefficients (ICCs). Kinematics were represented with and without correction for standing posture.

resultsMAE, MD, and precision of posture-corrected sCT kinematic results were 0.85, 0.60, and 0.71° for rotations and 0.40, 0.23, and 0.39 mm for translations, respectively. Accuracy of posture-corrected joint angles was within 0.17° of prior MBT validation in the hip, while translation accuracy and precision were greater herein. Kinematic results using CT and sCT had similar reliability.

conclusionThe results of this study establish novel reliability metrics for in vivo hip kinematics from BVR. Findings indicate that sCT can be used in lieu of CT to measure in vivo hip kinematics, reducing radiation burden of BVR hip kinematic protocols by up to 73%.

Indexed as

Hip JointModels, BiologicalTomography, X-Ray ComputedAdultBiomechanical PhenomenaFemaleGaitHumansMagnetic Resonance ImagingMaleBone-to-bone distanceHip kinematicsLimits of agreementMagnetic resonance imagingRadiation-freeRepeatability

Identifiers

PMID40849362
PMCPMC13094538

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.