ArticleSchizophrenia bulletin2025
Ketogenic Diet as Protection for Deprescribing Antipsychotics.
Article in Schizophrenia bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
People with schizophrenia or schizoaffective disorder are almost always treated with continued use of antipsychotics. Tapering of antipsychotics is very often associated with a recurrence of symptoms within a year. This applies particularly to the final steps of reduction from very small doses. Ketosis seems to offer protection against psychotic relapses in these final steps. I report a case series that supports this thesis. Two effects of antipsychotics that disappear after discontinuation of the medication and can be replaced by ketosis could possibly be responsible for this: effects on the mesolimbic system against the background of insufficient GABAergic inhibition in the prefrontal cortex and mesolimbic system; effects on the microglia against the background of increased unspecific neuroinflammation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.