Evidence map›Paper›PMID 40848211›Full record

ArticleApplied biochemistry and biotechnology2025

Evaluation of Benzothiazole-Chalcone Hybrids: Apoptosis Induction, Docking Analysis, and Anticancer Potential in Gastric Cancer Cells.

Ilker Kiliccioglu, Gorkem Dulger, Ahmad Badreddin Musatat, Alparslan Atahan, Emel Caliskan, Merve Alpay, Mustafa Zengin, Basaran Dulger

Abstract read
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In one paragraph

Article in Applied biochemistry and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ilker KilicciogluDepartment of Medical Biology, Faculty of Medicine, Duzce University, Konuralp, 81000, Duzce, Türkiye. i_kiliccioglu@yahoo.com.tr.ORCID http://orcid.org/0000-0003-3367-9665
Gorkem DulgerDepartment of Medical Biology, Faculty of Medicine, Duzce University, Konuralp, 81000, Duzce, Türkiye.ORCID http://orcid.org/0000-0002-9517-3830
Ahmad Badreddin MusatatDepartment of Chemistry, Faculty of Science, Sakarya University, Sakarya, Türkiye.ORCID http://orcid.org/0000-0002-4137-4901
Alparslan AtahanDepartment of Chemistry, Faculty of Arts and Science, Duzce University, Duzce, Türkiye.ORCID http://orcid.org/0000-0001-8904-9377
Emel CaliskanDepartment of Medical Microbiology, Faculty of Medicine, Duzce University, Duzce, Türkiye.ORCID http://orcid.org/0000-0003-3444-1579
Merve AlpayDepartment of Medical Biochemistry, Faculty of Medicine, Duzce University, Duzce, Türkiye.ORCID http://orcid.org/0000-0002-8782-9561
Mustafa ZenginDepartment of Chemistry, Faculty of Science, Sakarya University, Sakarya, Türkiye.ORCID http://orcid.org/0000-0002-0243-1432
Basaran DulgerDepartment of Biology, Faculty of Arts and Science, Duzce University, Duzce, Türkiye.ORCID http://orcid.org/0000-0002-3184-2652

Funding

Düzce Üniversitesi 2021.04.01.1227
6 · The paper itself

Abstract

This study investigated a series of chalcone derivatives containing benzothiazole groups (C1-7) for their antimicrobial, antioxidant, and anticancer potential against gastrointestinal cancer cell lines. The compounds showed the highest antiproliferative effect in AGS gastric cancer cells compared to HCT116 colon cancer and HepG2 hepatocellular carcinoma cells. Among the tested compounds, C3 and C4 exhibited the most potent antiproliferative effects (IC

Indexed as

Antineoplastic AgentsApoptosisBenzothiazolesChalconeChalconesMolecular Docking SimulationStomach NeoplasmsCell Line, TumorCell ProliferationHumansAntineoplastic AgentsbenzothiazoleBenzothiazolesChalconeChalconesADMEAGS gastric cancerApoptosisBenzothiazole-Chalcone hybridsDFTMolecular dockingRDG

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.