Evidence map›Paper›PMID 40847996›Full record

ArticleJournal of health and social behavior2026

A Life Course Perspective on Cognitive Aging: The Interplay between Early and Later Life Stimulating Environments.

Siyun Peng, Brea Perry

Abstract read
In one paragraph

Article in Journal of health and social behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Social connection and cognitive health: A review of concepts, measures, and research priorities.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Siyun PengUniversity of South Florida, Tampa, FL, USA.ORCID 0000-0002-4049-4485
Brea PerryIndiana University, Bloomington, IN, USA.ORCID 0000-0001-7869-7168

Funding

Understanding how social connectedness protects older adults' cognitive health: the role of social cognitionR01AG070931 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI KRENDL, ANNE CATHERINE, PERRY, BREA LOUISE · 2020 to 2024
$3.6M
Leveraging Neuroimaging Biomarkers to Understand the Role of Social Networks in Alzheimer's DiseaseR01AG057739 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI APOSTOLOVA, LIANA G, PERRY, BREA LOUISE · 2018 to 2022
$3.5M
Epigenetic mechanisms underlying the direct and moderating effects of social connectedness on complex diseases in agingR01AG076032 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI Brea Louise Perry · 2022 to 2026
$2.9M
Social Mechanisms of Cognitive Aging Disparities in Rural and Urban Older PopulationsR01AG078247 · NIA · OKLAHOMA STATE UNIVERSITY STILLWATER · PI Adam Ronald Roth · 2022 to 2026
$2.6M
Social Networks in Alzheimer Disease 2.0.R37AG057739 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI PERRY, BREA LOUISE · 2024 to 2025
$1.5M
NIA NIH HHS R01 AG057739NIA NIH HHS R01 AG070931NIA NIH HHS R01 AG076032NIA NIH HHS R01 AG078247NIA NIH HHS R37 AG057739
6 · The paper itself

Abstract

A gap in the literature on social determinants of cognitive aging is the lack of focus on the interplay of cognitively stimulating environments across the life course. This study uses a life course perspective to propose and examine potential interaction and mediation effects between early and later life stimulating environments. Using rich cognitive assessments and egocentric network data from the state-representative Person to Person Health Interview Study (N = 685) conducted in Indiana, we find that associations between social bridging network (later life stimulating environments) and cognitive outcomes are strongest for people with less than a high school education (early life stimulating environments), constituting a moderating compensatory leveling effect rather than an added protection effect. Regarding mediation, we find no evidence of a cumulative (dis)advantage effect in the context of cognitive aging. Overall, this study presents a useful theoretical framework to study the interplay of cognitively stimulating environments across the life course.

Indexed as

AgingCognitionCognitive AgingSocial EnvironmentSocial SupportAgedEducational StatusFemaleHumansIndianaMalecognitive agingeducationlife coursesocial network

Identifiers

PMID40847996
PMCPMC13285902

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.