Evidence map›Paper›PMID 40847824›Full record

ArticleElectrophoresis2025

Serum Proteinogram in the Free-Living Brazilian Common Opossum (Didelphis aurita).

Andrés Mauricio Ortega Orozco, Lucas Drumond Bento, Pollyanna Cordeiro Souto, Fabrícia Modolo Girardi, Verônica Rodrigues Castro, João Vitor Gonçalves de Oliveira, Camilo José Ramirez Lopez, Edvaldo Barros, Artur Kanadani Campos, Leandro Abreu da Fonseca

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Electrophoresis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrés Mauricio Ortega OrozcoVeterinary Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
Lucas Drumond BentoVeterinary Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
Pollyanna Cordeiro SoutoVeterinary Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
Fabrícia Modolo GirardiVeterinary Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
Verônica Rodrigues CastroVeterinary Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
João Vitor Gonçalves de OliveiraVeterinary Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
Camilo José Ramirez LopezVeterinary Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
Edvaldo BarrosBiomolecule Analysis Center (NuBioMol), Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
Artur Kanadani CamposVeterinary Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
Leandro Abreu da FonsecaVeterinary Clinical Pathology Laboratory at Veterinary Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Didelphis aurita is a synanthropic marsupial widely distributed in southeastern Brazil, known for its resistance to venom and its relevance in biomedical research. This study aimed to characterize the serum proteinogram of free-living D. aurita individuals. Blood samples from 27 animals, classified as "healthy" or "diseased," were analyzed. Eighteen protein bands were identified, with molecular weights ranging from 24 to 242 kDa. Among these, variations in specific bands were associated with health status (band J), sex (bands D, M, N, and P), and age (bands N and P). Mass spectrometry (liquid chromatography-tandem mass spectrometry [LC-MS/MS]) identified seven proteins, including DM64, ceruloplasmin, von Willebrand factor A (VWFA) domain protein, alpha-2-macroglobulin, fibronectin, and actin depolymerizing factor. These results highlight the influence of biological factors on serum protein profiles and reinforce the potential of D. aurita as a model for immunological and proteomic studies.

Indexed as

Blood ProteinsDidelphisAnimalsBrazilChromatography, LiquidFemaleMaleTandem Mass SpectrometryBlood ProteinsLC–MSproteomicsodium dodecyl sulfate‐polyacrylamide gel electrophoresis (SDS‐PAGE)wildlife

Identifiers

PMID40847824
PMCPMC12532081

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.