Evidence map›Paper›PMID 40847577›Full record

SynthesisJournal of advanced nursing2026

Clinical Trials in Central Venous Access Devices: An Evidence and Gap Map.

Mari Takashima, Areum Hyun, Tricia Kleidon, Victoria Gibson, Sabrina De Souza, Elouise Comber, Jacqueline Cunninghame, Jefferson Wildes da Silva Moura, Martha Mansah, Deanne August and 5 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of advanced nursing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mari TakashimaSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0002-1167-9106
Areum HyunSchool of Nursing and Midwifery, Griffith University, Brisbane, Queensland, Australia.
Tricia KleidonSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0001-8369-3970
Victoria GibsonSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.
Sabrina De SouzaSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0002-3628-0134
Elouise ComberSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.
Jacqueline CunninghameSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.
Jefferson Wildes da Silva MouraSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0002-7192-1099
Martha MansahSchool of Nursing and Midwifery, Griffith University, Brisbane, Queensland, Australia.
Deanne AugustSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0002-7204-7065
Patrícia Kuerten RochaNursing Post-Graduation Program (PEN), Universidade Federal de Santa Catarina (UFSC), Santa Catarina, Brazil.
Nicole MarshNursing and Midwifery Research Centre, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-5779-1304
Amanda CorleySchool of Nursing and Midwifery, Griffith University, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-4250-4077
Sam KeoghSchool of Nursing and Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-2797-4388
Amanda UllmanSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0001-8860-5319

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo systematically map the landscape of central venous access device research from 2014 to 2024, identifying critical gaps in evidence that may impact nursing practice and patient outcomes across the full device lifecycle from selection through to removal.

designThis review was conducted in accordance with the Guidance for producing a Campbell evidence and gap map and reported following Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidelines. DATA SOURCES: PubMed, Cumulative Index to Nursing and Allied Health Literature Complete, Scopus, and Cochrane Central Register of Controlled Trials were systematically searched with additional hand-searching of reference lists from included reviews.

methodsWe systematically reviewed literature published between 2014 and 2024, mapping 710 studies on central venous access device interventions and outcomes. Studies were categorised by design, population, setting, device characteristics, intervention types, and outcomes. Evidence was evaluated using the National Health and Medical Research Council levels of evidence framework.

resultsOf 710 included studies, 89 were systematic reviews and 621 primary studies, of which 41.1% (n = 292) were randomised controlled trials. Research was primarily conducted in high-income countries (n = 405, 65.2%) and focused on adults (n = 370, 59.6%) in hospital inpatient settings (n = 588, 94.7%). Catheter insertion and infection prevention dominated the evidence base, while device selection and removal procedures were less studied. Infection outcomes were extensively reported (bloodstream infection: n = 455, 13.6% of 3349 outcomes), while patient-reported outcomes (n = 218, 6.5%) and cost (n = 60, 1.8%) were underrepresented.

conclusionsThis review reveals that central venous access device research is predominantly focused on insertion and infection prevention while other key parts of nursing practice are under-supported. IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE: Future nursing research should address these gaps to improve evidence-based care across diverse populations and healthcare contexts, particularly focusing on understudied device types, settings, and vulnerable populations. REPORTING

methodThis review was conducted and reported in accordance with the Guidance for producing a Campbell evidence and gap map. PATIENT OR PUBLIC CONTRIBUTION: This study did not include patient or public involvement in its design, conduct, or reporting.

Indexed as

Catheterization, Central VenousCentral Venous CathetersClinical Trials as TopicAdultHumanscentral venous access devicesevidence and gap mapnursingscoping reviewsystematic review

Identifiers

PMID40847577
PMCPMC13069238

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.