Evidence map›Paper›PMID 40847492›Full record

ArticleJournal of the American Heart Association2025

Health Care Resource Use and Economic Burden in Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy and Atrial Fibrillation.

John C Stendahl, Sounok Sen, Michael Butzner, Eros Papademetriou, Ravi Potluri, Xing Liu, Daniel Jacoby, James V Freeman

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

John C StendahlSection of Cardiovascular Medicine Yale School of Medicine New Haven CT USA.ORCID 0000-0002-1568-9280
Sounok SenSection of Cardiovascular Medicine Yale School of Medicine New Haven CT USA.ORCID 0000-0002-1806-3566
Michael ButznerCytokinetics Incorporated South San Francisco CA USA.
Eros PapademetriouPutnam Associates, LLC Boston MA USA.
Ravi PotluriPutnam Associates, LLC Boston MA USA.ORCID 0000-0002-0509-2659
Xing LiuPutnam Associates, LLC Boston MA USA.
Daniel JacobyCytokinetics Incorporated South San Francisco CA USA.
James V FreemanSection of Cardiovascular Medicine Yale School of Medicine New Haven CT USA.ORCID 0000-0002-4614-6879

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is common among patients with obstructive hypertrophic cardiomyopathy (oHCM), although the impact of AF on health care resource use and costs is not well defined.

methodsWe performed a retrospective analysis of claims data from 2016 to 2021 and used

resultsOf 22 216 patients with symptomatic oHCM, 6677 had prevalent AF (30.1%), 2879 had incident AF (13.0%), and 12 660 were without AF (57.0%). Patients with incident AF incurred mean total health care costs that were similar to those with prevalent AF but substantially greater than those without AF (mean, $66 619 [95% CI, $59 702-$74 336] versus $63 937 [95% CI, $59 803-$68 356] versus $46 686 [95% CI, $43 901-$49 648] per person per year,

conclusionsThe diagnosis of AF in the setting of symptomatic oHCM not only has important implications for patient management but also substantial economic impacts, as it is associated with significantly greater health care costs and resource use relative to patients with symptomatic oHCM and no AF.

Indexed as

Atrial FibrillationCardiomyopathy, HypertrophicCost of IllnessHealth Care CostsHealth ResourcesAdultAgedFemaleHospitalizationHumansIncidenceMaleMiddle AgedPrevalenceRetrospective StudiesUnited Statesatrial fibrillationhealth care costshealth care resource usehypertrophic cardiomyopathyobstructive hypertrophic cardiomyopathy

Identifiers

PMID40847492
PMCPMC12553423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.