Evidence map›Paper›PMID 40847453›Full record

ArticleBrain and behavior2025

Metabolic Remapping at "Point-Line-Plane" Levels With Central Dysfunction in Cerebral Small Vessel Disease.

Jie Ma, Juan-Juan Lu, Xin Gao, Jia-Jia Wu, Xiang-Xin Xing, Mou-Xiong Zheng, Xu-Yun Hua, Jian-Guang Xu

Abstract read
In one paragraph

Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jie MaDepartment of Rehabilitation Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID https://orcid.org/0000-0003-0451-7923
Juan-Juan LuDepartment of Rehabilitation Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xin GaoUniversal Medical Imaging Diagnostic Center, Shanghai, China.
Jia-Jia WuDepartment of Rehabilitation Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xiang-Xin XingDepartment of Rehabilitation Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Mou-Xiong ZhengDepartment of Traumatology and Orthopedics, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xu-Yun HuaDepartment of Traumatology and Orthopedics, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jian-Guang XuDepartment of Rehabilitation Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID https://orcid.org/0000-0003-0601-3403

Funding

National Natural Science Foundation of China 82172554National Natural Science Foundation of China 82272583National Natural Science Foundation of China 82272589National Natural Science Foundation of China 82302870Science & Technology Development Fund of Shanghai University of Traditional Chinese Medicine 23KFL112the National Key R&D Program of China 2018YFC2001600the National Key R&D Program of China 2018YFC2001604
6 · The paper itself

Abstract

backgroundThis study is aimed at investigate the glucose metabolic patterns of cerebral small vessel disease (CSVD) at "point-line-plane" levels.

methodsWe retrospectively collected the

resultsIncreased SUV

conclusionAffected by CSVD, the glucose metabolism redistribution is heterogeneous in different brain network, and its changes start from brain region and metabolic connectivity within the sub-brain network.

Indexed as

BrainCerebral Small Vessel DiseasesAgedFemaleFluorodeoxyglucose F18GlucoseHumansMagnetic Resonance ImagingMaleMiddle AgedNerve NetPositron-Emission TomographyRetrospective StudiesFluorodeoxyglucose F18Glucosebrain networkscerebral small vessel diseaseglucose metabolismmetabolic connectivity

Identifiers

PMID40847453
PMCPMC12373711

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.