Evidence map›Paper›PMID 40847418›Full record

ArticleBrain and behavior2025

Clinical Characteristics Analysis of Vestibular Migraine Combined With Unruptured Intracranial Aneurysm.

Yaoheng Zhang, Yi Ju, Chunling Liu, Hui Li, Yanlu Jia, Shuning Sun, Haozhe Yin, Suisui Ma, Wenbo Peng

Abstract read
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Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yaoheng ZhangDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID https://orcid.org/0009-0005-7364-854X
Yi JuDepartment of Neurology, Beijing Tiantan Hospital, Beijing, China.
Chunling LiuDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Hui LiDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yanlu JiaDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shuning SunDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Haozhe YinDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Suisui MaDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wenbo PengDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with vestibular migraine (VM) and those with migraine accompanied by unruptured intracranial aneurysm (UIA) may face an increased risk of UIA rupture. This study investigated the rupture risk of UIA in patients with VM and proposed a plausible explanation for the associations between VM, migraine, and UIA distribution, particularly concerning interactions within vascular and nociceptive conduction pathways.

methodsA cross-sectional case-control study involving 148 subjects diagnosed with UIA was conducted, who were categorized into three groups: the VM, the migraine, and the control groups. The distribution of parent arteries and the morphological parameters of the UIA, such as diameter, size, depth, neck width, mean parent arterial diameter, size ratio, non-spherical index (NSI), and parameters specific to bifurcation UIA, were extracted from the original imaging data and 3D-Slicer software for intergroup comparison.

resultsUIA was predominantly located in the internal carotid arteries (ICA) at C4 (12.3%), C5 (14.0%), and C7 (35.1%) in the VM group. The migraine group exhibited UIA primarily in the ICA at C6 (42.2%) and the vertebrobasilar artery (10.9%). In the control group, UIA was concentrated in the middle cerebral artery (22.6%). These distributions differed significantly (p

conclusionsWe observed significant differences in the distribution of UIA between the VM and migraine groups compared to the control group. Furthermore, intergroup comparisons of morphological parameters indicated that both VM and migraine patients have a higher risk of aneurysm rupture. We propose a plausible hypothesis regarding the relationship between VM, migraine, and UIA distribution. Future research should involve more precise hemodynamic analyses, long-term patient follow-up, and potential animal studies.

Indexed as

Intracranial AneurysmMigraine DisordersAdultAneurysm, RupturedCarotid Artery, InternalCase-Control StudiesCross-Sectional StudiesFemaleHumansMaleMiddle Aged3D‐Sliceraneurysm ruptureintracranial aneurysmmigrainevestibular migraine

Identifiers

PMID40847418
PMCPMC12373513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.