Evidence map›Paper›PMID 40847341›Full record

SynthesisBMC public health2025

Effects of air pollutants on the incidence, progression, and mortality of idiopathic pulmonary fibrosis: a systematic review and meta-analysis.

Cheng Luo, Xinhui Wu, Shipeng Zhang, Junwen Tan, Xingling Song, Bo Ning, Qi Tang, Yuzhi Huo, Jiajie Li, Yuanhang Ye and 1 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Whole exome sequencing identified two novel mutations ofFrontiers in cell and developmental biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cheng Luo *Chengdu University of Traditional Chinese Medicine, Chengdu, 610032, China.ORCID http://orcid.org/0000-0003-4265-6537
Xinhui Wu *Chengdu University of Traditional Chinese Medicine, Chengdu, 610032, China.
Shipeng Zhang *Chengdu University of Traditional Chinese Medicine, Chengdu, 610032, China.
Junwen TanChengdu University of Traditional Chinese Medicine, Chengdu, 610032, China.
Xingling SongChengdu Integrated Traditional Chinese Medicine & Western Hospital, Chengdu, 610072, China.
Bo NingDepartment of Cardiovascular Surgery, Guangdong Provincial Hospital of Chinese Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, the Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Qi TangChengdu University of Traditional Chinese Medicine, Chengdu, 610032, China.
Yuzhi HuoChengdu University of Traditional Chinese Medicine, Chengdu, 610032, China.
Jiajie LiYunnan University of Chinese Medicine, Kunming, 650500, China.
Yuanhang YePengzhou Third People's Hospital, Chengdu, 611931, China. yyh421492693@outlook.com.ORCID http://orcid.org/0009-0008-6230-1163
Fei WangChengdu University of Traditional Chinese Medicine, Chengdu, 610032, China. wangfei631010@163.com.

Funding

Joint Innovation Fund of Health Commission of Chengdu and Chengdu University of Traditional Chinese Medicine 2024120973National Natural Science Foundation of China 82174347National Science and Technology Major Project 2020YFC2003104
6 · The paper itself

Abstract

backgroundThe widespread distribution of air pollutants poses a major challenge to global public health, causing a range of health problems, including the incidence and progression of idiopathic pulmonary fibrosis (IPF). This study aims to provide insights into the specific effects of air pollutants on the risk of IPF through a systematic evaluation and meta-analysis approach.

methodsThe present study was conducted through a comprehensive search of four data-Embase, Web of Science, PubMed, and Cochrane Library-from their inception to 25th November 2024, limited to English-language literature. To assess the potential relationship between a wide range of air pollutants and IPF, a random effects model was used to estimate the risk factors in this study. In addition, subgroup analyses of the data according to age, sex, smoking habits, and geographic location were performed, with the aim of exploring the relationship between air pollutants and the risk of IPF in different populations.

resultA total of 17 papers covering 14 countries were included in this study, totaling 18 studies involving 858,557 participants and 25,968 event occurrences. Our systematic evaluation and meta-analysis showed an increased risk of IPF disease progression for every 5 µg/m

conclusionsThis study found that NO

Indexed as

Air PollutantsEnvironmental ExposureIdiopathic Pulmonary FibrosisDisease ProgressionHumansIncidenceParticulate MatterRisk FactorsAir PollutantsParticulate MatterAir pollutantsIdiopathic pulmonary fibrosisMeta-analysisRiskSystematic evaluation

Identifiers

PMID40847341
PMCPMC12372251

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.