Evidence map›Paper›PMID 40847226›Full record

ReviewCancer treatment and research2025

Cancer Immunotherapy-An Overview.

Prakash Kulkarni, Dana Do, Sagun Shrestha, Benjamin Leach, Ravi Salgia

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cancer treatment and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Prakash KulkarniDepartment of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA, USA.
Dana DoDepartment of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA, USA.
Sagun ShresthaCity of Hope Phoenix, Goodyear, AZ, USA.
Benjamin LeachDepartment of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Mission Hills, CA, USA.
Ravi SalgiaDepartment of Medical Oncology and Therapeutics Research, City of Hope ComprehensiveCancer Center, Duarte, CA, USA. rsalgia@coh.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy has had a profound impact on how we treat cancer. Immunotherapy takes advantage of the body's immune system to combat the disease and is considered as one of the pillars of cancer care together with chemotherapy, radiation therapy, and surgery. This introductory chapter provides a brief overview of the different types of cancer immunotherapies currently available, their mechanisms of action, and the benefits and potential side effects. Despite the success of these emerging therapies, resistance remains a genuine concern. Thus, mechanisms of resistance to immunotherapy are also briefly discussed. In addition, an overview of the various combination therapies such as chemotherapy, radiation therapy, and targeted therapy, that are currently used in combination with cancer immunotherapy, is presented. Finally, the chapter highlights how a "Team Medicine" approach could enable all eligible cancer patients to receive this promising treatment to treat their respective cancer types. More, detailed information regarding the different immunotherapies as well as their combinations when applicable in different cancers is discussed in the ensuing chapters dedicated to individual cancer type.

Indexed as

ImmunotherapyNeoplasmsHumansCancer immunotherapyImmunotherapy resistanceNon-genetic mechanismsPhenotypic plasticity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.