Evidence map›Paper›PMID 40847038›Full record

ArticleScientific reports2025

Biotechnological potential of Cannabis sativa adventitious roots for producing immunomodulatory and anti-inflammatory bioactive compounds.

Su Hyun Park, Jeong Moo Han, Yun Hye Kim, Hyeon Jin Lee, Young Bae Ryu, Hyung Won Ryu, Jae Cheol Jeong, Seon Min Oh, Woo Sik Kim

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Su Hyun Park *Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup-si, 56212, Jeollabuk-do, Republic of Korea.
Jeong Moo Han *Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Yun Hye KimFunctional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup-si, 56212, Jeollabuk-do, Republic of Korea.
Hyeon Jin LeeFunctional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup-si, 56212, Jeollabuk-do, Republic of Korea.
Young Bae RyuFunctional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup-si, 56212, Jeollabuk-do, Republic of Korea.
Hyung Won RyuNatural Product Research Center and Natural Product Central Bank, Korea Research Institute of Bioscience and Biotechnology, Cheongju-si, 28116, Republic of Korea.
Jae Cheol JeongBiological Resource Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup-si, 56212, Jeollabuk-do, Republic of Korea. jcjeong@kribb.re.kr.
Seon Min OhNatural Product Research Center and Natural Product Central Bank, Korea Research Institute of Bioscience and Biotechnology, Cheongju-si, 28116, Republic of Korea. seonmin88@kribb.re.kr.
Woo Sik KimFunctional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup-si, 56212, Jeollabuk-do, Republic of Korea. kws6144@kribb.re.kr.

Funding

Korea Research Institute of Bioscience and Biotechnology Research Initiative Programs KGM1052511Korea Research Institute of Bioscience and Biotechnology Research Initiative Programs KGM5382521
6 · The paper itself

Abstract

Cannabis sativa L. (C. sativa), commonly known as hemp, is widely recognized for its diverse range of bioactive compounds with therapeutic potential in medicinal, industrial, and nutritional applications. This study investigates the use of adventitious roots (ARs) derived from C. sativa as a scalable platform for producing bioactive metabolites with immunomodulatory and anti-inflammatory properties. We first isolated extracts from C. sativa ARs (CS-AR) using various solvents: methanol (MeOH-E), chloroform (CHCl

Indexed as

Anti-Inflammatory AgentsCannabisImmunologic FactorsPlant ExtractsPlant RootsAnimalsBiotechnologyCannabinoidsDendritic CellsMiceAnti-Inflammatory AgentsCannabinoidsImmunologic FactorsPlant ExtractsAdventitious rootsAnti-inflammatory activityCannabis sativa L.Dendritic cellsImmunosuppressionT cells

Identifiers

PMID40847038
PMCPMC12373723

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.