Evidence map›Paper›PMID 40846956›Full record

ArticleAIDS research and therapy2025

Prevalence and predictors of cardiovascular disease risk among people living with human immunodeficiency virus in Nigeria.

Abiodun Isah, Olujuwon Ibiloye, Temiwoluwa Omole, Oluwatobi Olaniyi, Plang Jwanle, Ifeyinwa Onwuatelo, Jay Osi Samuels, Prosper Okonkwo

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Article in AIDS research and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Abiodun IsahAPIN Public Health Initiatives, Plot 1551, Zone E, Apo Resettlement, Apo, Abuja, Ogun State, Nigeria. aisah@apin.org.ng.
Olujuwon IbiloyeAPIN Public Health Initiatives, Plot 1551, Zone E, Apo Resettlement, Apo, Abuja, Ogun State, Nigeria.
Temiwoluwa OmoleAPIN Public Health Initiatives, Plot 1551, Zone E, Apo Resettlement, Apo, Abuja, Ogun State, Nigeria.
Oluwatobi OlaniyiAPIN Public Health Initiatives, Plot 1551, Zone E, Apo Resettlement, Apo, Abuja, Ogun State, Nigeria.
Plang JwanleAPIN Public Health Initiatives, Plot 1551, Zone E, Apo Resettlement, Apo, Abuja, Ogun State, Nigeria.
Ifeyinwa OnwuateloAPIN Public Health Initiatives, Plot 1551, Zone E, Apo Resettlement, Apo, Abuja, Ogun State, Nigeria.
Jay Osi SamuelsAPIN Public Health Initiatives, Plot 1551, Zone E, Apo Resettlement, Apo, Abuja, Ogun State, Nigeria.
Prosper OkonkwoAPIN Public Health Initiatives, Plot 1551, Zone E, Apo Resettlement, Apo, Abuja, Ogun State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdvances in HIV/AIDS treatment have transformed HIV into a manageable chronic condition. However, cardiovascular disease (CVD) and other non-communicable diseases are increasingly emerging among people living with HIV (PLHIV), especially in developing countries. This study assessed the prevalence and determinants of CVD risk among PLHIV in Nigeria.

methodsA cross-sectional study was conducted from February to May 2024 across ten Nigerian health facilities, involving 1,000 PLHIV on antiretroviral therapy (ART). Data on socio-demographic characteristics, lifestyle behaviors, family history of CVD, and HIV-related clinical factors were collected through structured questionnaires and medical records. Chi-square tests and logistic regression analyses were conducted using SPSS v24, with significance set at p < 0.05.

resultsParticipants had a median age of 48 years (IQR: 41-56), and 60.7% were female. Hypertension (26.2%), overweight (27.9%), high-risk waist-hip ratio (39.6%), and obesity (19.6%) were common. Overall, 61.1% were at risk for CVD. Significant predictors of higher CVD risk included urban residence (aOR: 1.48; 95% CI: 1.13-1.94), smoking (aOR: 2.16; 95% CI: 1.26-3.68), family history of hypertension (aOR: 1.7; 95% CI: 1.2-2.4), being on ART for ≥ 10 years (aOR: 1.5; 95% CI: 1.1-2.01), and infrequent consumption of high-fat, sugar, and salt (HFSS) foods (aOR: 1.4; 95% CI: 1.1-1.9). Conversely, being retired or a student was associated with lower risk.

conclusionCVD risk is prevalent among PLHIV in Nigeria and is linked to demographic, clinical, and lifestyle factors. Targeted, integrated interventions, and client-centered care strategies are required to reduce CVD burden among PLHIV.

Indexed as

Cardiovascular DiseasesHIV InfectionsAdultCross-Sectional StudiesFemaleHeart Disease Risk FactorsHumansHypertensionLife StyleMaleMiddle AgedNigeriaPrevalenceRisk FactorsCardiovascular disease (CVD)Cardiovascular risk factorsHIV-associated cardiovascular riskHuman immunodeficiency virus (HIV)NigeriaNon-Communicable diseases (NCDs)People living with HIV (PLHIV)

Identifiers

PMID40846956
PMCPMC12372355

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.