Evidence map›Paper›PMID 40846942›Full record

ArticleJournal of translational medicine2025

Associations among skin carotenoids, anthropometric parameters and healthy lifestyle behaviors in young adults: a cross-sectional, population-based study.

Giuseppina Augimeri, Danilo Lofaro, Adele Vivacqua, Ines Barone, Cinzia Giordano, Catia Morelli, Domenico Conforti, Diego Sisci, Stefania Catalano, Daniela Bonofiglio and 1 more

Abstract read
In one paragraph

Article in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giuseppina AugimeriDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Arcavacata di Rende, Cosenza, Italy.
Danilo LofaroDepartment of Mathematics and Computer Science, University of Calabria, 87036, Arcavacata di Rende, Cosenza, Italy.
Adele VivacquaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Arcavacata di Rende, Cosenza, Italy.
Ines BaroneDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Arcavacata di Rende, Cosenza, Italy.
Cinzia GiordanoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Arcavacata di Rende, Cosenza, Italy.
Catia MorelliDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Arcavacata di Rende, Cosenza, Italy.
Domenico ConfortideHealth Lab, Department of Mechanical, Energetic, Management Engineering, University of Calabria, 87036, Arcavacata di Rende, Cosenza, Italy.
Diego SisciDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Arcavacata di Rende, Cosenza, Italy.
Stefania CatalanoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Arcavacata di Rende, Cosenza, Italy.
Daniela BonofiglioDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Arcavacata di Rende, Cosenza, Italy. daniela.bonofiglio@unical.it.ORCID 0000-0002-4142-0496
MeDiet Working Group

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca CUP H53D23006420006Ministero dell'Istruzione, dell'Università e della Ricerca CUP H53D23010120001)Ministero dell'Istruzione, dell'Università e della Ricerca Department of Excellence (Italian Law. 232/2016)Ministero dell'Istruzione, dell'Università e della Ricerca European Union; NextGeneration EU (# 2022AA4FTJMinistero dell'Istruzione, dell'Università e della Ricerca PRIN 2022Ministero dell'Istruzione, dell'Università e della Ricerca PRIN PNRR 2022-European Union; NextGenerationEU initiative (#P2022YAKJY
6 · The paper itself

Abstract

backgroundHealthy lifestyle behaviors are the cornerstone for the prevention of a wide range of metabolic and chronic non-communicable diseases (NCSs). Among lifestyle factors, diet, body mass index (BMI), smoking habits and physical activity are associated with the risk of developing NCSs, including obesity, type 2 diabetes, cardiovascular diseases and certain types of cancer. Particularly, as a part of a healthy diet, increased intake of fruit and vegetable (FV), rich sources of vitamins and minerals, dietary fiber and non-nutrient substances including antioxidants, are known to improve overall health. Carotenoid levels can be measured in skin providing an objective biomarker of long-term FV intake. This study aimed to explore the potential role of skin carotenoids as indicators of health status examining their associations with lifestyle factors among a cohort of young adults. This study aimed to explore the potential role of skin carotenoids as indicators of health status examining their associations with lifestyle factors among a cohort of young adults.

methodsA sample of 2078 university students were enrolled at the University of Calabria, Italy. All participants underwent anthropometric measurements, assessment of the adherence to the Mediterranean Diet (MD) pattern by the Mediterranean Diet Adherence Screener (MEDAS) and Mediterranean Life Style Index (MEDLIFE) questionnaires and the skin carotenoid content by Veggie Meter®. Student's t-test, chi-squared test, and univariate and multiple linear regressions were used for analyses.

resultsParticipants had a mean BMI of 23.30 ± 3.79, which falls within the normal range as well as a medium adherence to the dietary (MEDAS: 7.19 ± 1.86) and lifestyle (MEDLIFE: 3.38 ± 1.21) MD patterns. Mean skin carotenoid levels were 360.61 ± 97.02, with higher carotenoid score in participants stocking up on FV from garden than market (368.28 ± 99.98 vs 357.84 ± 95.88, p = 0.03). Moreover, skin carotenoids were significantly higher in participants declaring to consume more than 2 servings of vegetables and more than 3 servings of fruits/day compared to those having less FV intakes (391.67 ± 101.03 vs 349.27 ± 90.92, p < 0.0001). Multiple regression analyses have revealed that the carotenoid score was positively associated with age, male gender, MEDAS, stocking up on FV from the garden and consuming high FV, while it was negatively associated with BMI and smoking habits.

conclusionsSkin carotenoids are objective indicators of health status showing a positive association with the adherence to healthy diet and lifestyle behaviors among a cohort of young adults. Findings from this study may contribute to identify individuals with potential risk factors for NCDs and to develop public health strategies to encourage healthier lifestyles.

Indexed as

AnthropometryCarotenoidsHealthy LifestyleSkinAdultCross-Sectional StudiesFemaleHumansMaleYoung AdultCarotenoidsFruit and vegetable intakeMediterranean DietSkin carotenoid levelsVeggie meter

Identifiers

PMID40846942
PMCPMC12372304

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.