ArticleBMC plant biology2025
Harnessing the antioxidant and cytoprotective power of Aitchisonia rosea: phytochemical insights and mechanistic validation.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Targeting oxidative stress and neurodegeneration: the role of Putranjiva roxburghii in Alzheimer's.Inflammopharmacology · 2026Review
- Effects of red palm oil intervention on serum lipids, hepatic antioxidant capacity and gut microbiota in high-fat diet-fed mice.Open life sciences · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAitchisonia rosea (A. rosea), traditionally used for oxidative stress-related conditions, lacks comprehensive scientific validation of its antioxidant mechanisms and cellular protective effects. This study aimed to meticulously investigate the phytochemical composition, in vitro antioxidant capacity, and protective efficacy of A. rosea extracts and essential oil against oxidative damage in biomolecular and cellular models.
resultsAnalysis of the essential oil by gas chromatography-mass spectrometry (GC-MS) identified key bioactive components, including sesquiterpenes (e.g., germacrene, beta-caryophyllene) and oxygenated monoterpenes (e.g., carvacrol, linalool). Various solvent extracts, particularly methanol, ethyl acetate, and n-butanol fractions, along with the essential oil, demonstrated potent antioxidant activities across multiple assays including radical scavenging (DPPH), reducing power (FRAP), and Trolox equivalent antioxidant capacity (TEAC), indicating significant free radical neutralisation capabilities. Crucially, these samples provided substantial protection against hydrogen peroxide (H
conclusionsThe findings substantiate the remarkable antioxidant and cytoprotective potential of A. rosea, primarily attributed to its rich array of polyphenolic, flavonoid, and terpenoid compounds. The demonstrated ability to safeguard both DNA and erythrocyte membranes from oxidative insults establishes A. rosea as a scientifically validated candidate for further pharmaceutical and industrial development, particularly for applications targeting oxidative stress-mediated diseases.
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