Evidence map›Paper›PMID 40845333›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Associations of High Attenuation Area-Related Proteomic Biomarkers with Fibrotic or Subpleural Interstitial Lung Abnormalities.

John S Kim, Catherine L Debban, Daniel E Guzman, Riley T Hannan, Mary Salvatore, Claire McGroder, David Zhang, Anna J Podolanczuk, Daniel A Duprez, Shwu-Fan Ma and 22 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

32 authors.

John S KimDepartment of Medicine.
Catherine L DebbanDepartment of Genome Sciences, and.
Daniel E GuzmanDepartment of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
Riley T HannanDepartment of Medicine.ORCID 0000-0003-0403-792X
Mary SalvatoreDepartment of Radiology, Jacobi Medical Center, Bronx, New York, New York.
Claire McGroderDepartment of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
David ZhangDepartment of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.ORCID 0000-0002-2983-9796
Anna J PodolanczukDivision of Pulmonary and Critical Care Medicine, Weill Cornell Medical Center, New York, New York.ORCID 0000-0002-9559-1485
Daniel A DuprezCardiovascular Division, Department of Medicine, School of Medicine, University of Minnesota, Minneapolis, Minnesota.
Shwu-Fan MaDepartment of Medicine.ORCID 0000-0002-3058-9480
Yong HuangDepartment of Medicine.
Jeffrey M SturekDepartment of Medicine.
Stephen S RichDepartment of Genome Sciences, and.
Jerome I RotterDepartment of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California.
Rajat DeoDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Ruth F DubinDepartment of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Janelle Vu PugashettiDepartment of Medicine, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-8889-2757
Jennifer M WangDepartment of Medicine, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-4670-7549
MeiLan K HanDepartment of Medicine, University of Michigan, Ann Arbor, Michigan.
Justin M OldhamDepartment of Medicine, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-4957-8869
Imre NothDepartment of Medicine.
Prescott G WoodruffDepartment of Medicine, University of California, San Francisco, San Francisco, California.
Victor E OrtegaDepartment of Medicine, Mayo Clinic, Phoenix, Arizona.
Julie C Fanburg-SmithDepartment of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia.
Edward B StelowDepartment of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia.
Christopher A MoskalukDepartment of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia.
Eric A HoffmanDepartments of Radiology, Medicine, and Biomedical Engineering, University of Iowa Carver College of Medicine, Iowa City, Iowa.ORCID 0000-0001-8456-9437
Christine Kim GarciaDepartment of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.ORCID 0000-0002-0771-1249
Russell P BowlerGenomic Medicine Institute, Cleveland Clinic, Cleveland, Ohio; and.
Peter GanzDepartment of Medicine, University of California, San Francisco, San Francisco, California.
R Graham BarrDepartment of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
Ani ManichaikulDepartment of Genome Sciences, and.

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MILES Frome WILKINSON · 2003 to 2026
$40.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
SPIROMICS II: Biological underpinnings of COPD heterogeneity and progressionU01HL137880 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, PRESCOTT G · 2017 to 2021
$27.9M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
PULMONARY CELLULAR AND MOLECULAR BIOLOGY TRAININGT32HL007749 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Robert Pickett Dickson · 1993 to 2026
$19.9M
Pulmonary microvascular perfusion in the Multi-Ethnic Study of AtherosclerosisR01HL077612 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI R Graham BARR · 2004 to 2026
$18.8M
Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary Disease (COPD)R01HL093081 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI R Graham BARR · 2008 to 2026
$17.2M
Task Area A Core Study Operations.Task Area A shall encompass annual follow-up of cohort members, clinical endpoints ascertainment, study coordination activities, maintenance of the database and biosp75N92020D00001 · NHLBI · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, ROBYN LEAGH · 2020 to 2025
$17.2M
CHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5M
AstraZenecaBellerophon TherapeuticsBoehringer IngelheimChiesi FarmaceuticiForest Research InstituteGlaxoSmithKlineGrifolsIkariaNCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1 TR001881NHLBI NIH HHS 75N92020D00001NHLBI NIH HHS 75N92020D00002NHLBI NIH HHS 75N92020D00003NHLBI NIH HHS 75N92020D00004NHLBI NIH HHS 75N92020D00005NHLBI NIH HHS 75N92020D00006NHLBI NIH HHS 75N92020D00007NHLBI NIH HHS and R01-HL179312NHLBI NIH HHS DK063491NHLBI NIH HHS F32 HL170760NHLBI NIH HHS F32HL170760NHLBI NIH HHS F32 HL175973NHLBI NIH HHS F32HL175973NHLBI NIH HHS HHSN268200900013CNHLBI NIH HHS HHSN268200900014CNHLBI NIH HHS HHSN268200900015CNHLBI NIH HHS HHSN268200900016CNHLBI NIH HHS HHSN268200900017CNHLBI NIH HHS HHSN268200900018CNHLBI NIH HHS HHSN268200900019CNHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS HSN268200900020CNHLBI NIH HHS K23 HL150301NHLBI NIH HHS K23-HL-150301NHLBI NIH HHS K23 HL171871NHLBI NIH HHS K24 HL137013NHLBI NIH HHS L30 HL181822NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS N01-HC-95159NHLBI NIH HHS N01-HC-95160NHLBI NIH HHS N01-HC-95161NHLBI NIH HHS N01-HC-95162NHLBI NIH HHS N01-HC-95163NHLBI NIH HHS N01-HC-95164NHLBI NIH HHS N01-HC-95165NHLBI NIH HHS N01-HC-95166NHLBI NIH HHS N01-HC-95167NHLBI NIH HHS N01-HC-95168NHLBI NIH HHS N01-HC-95169NHLBI NIH HHS R01 HL077612NHLBI NIH HHS R01-HL077612NHLBI NIH HHS R01 HL093081NHLBI NIH HHS R01-HL093081NHLBI NIH HHS R01 HL103676NHLBI NIH HHS R01-HL103676NHLBI NIH HHS R01 HL105756NHLBI NIH HHS R01-HL105756NHLBI NIH HHS R01-HL137880NHLBI NIH HHS R01 HL159081NHLBI NIH HHS R01-HL159081NHLBI NIH HHS R01 HL166290NHLBI NIH HHS R01 HL169166NHLBI NIH HHS R01 HL176659NHLBI NIH HHS R01 HL179312NHLBI NIH HHS RC1 HL100543NHLBI NIH HHS RC1-HL100543NHLBI NIH HHS T32 HL007749NHLBI NIH HHS T32HL007749NHLBI NIH HHS U01 HL137880NHLBI NIH HHS UL1-TR-000040NHLBI NIH HHS UL1-TR-001079NHLBI NIH HHS UL1-TR-001420NHLBI NIH HHS UL1-TR001881NIDDK NIH HHS P30 DK063491NIEHS NIH HHS P30 ES005605NovartisNycomedRegeneron PharmaceuticalsSanofiTakeda Pharmaceutical Company
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood ProteinsLung Diseases, InterstitialPulmonary FibrosisTomography, X-Ray ComputedAgedAged, 80 and overBiomarkersFemaleHumansLungMaleMiddle AgedProteomicsBiomarkersBlood Proteinsinterstitial lung diseaseproteomicsradiomics

Identifiers

PMID40845333
PMCPMC12555059

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.