Evidence map›Paper›PMID 40845273›Full record

ArticleJournal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association2025

Health-Related Values Discussions With Patients Receiving Allogeneic and Autologous Stem Cell Transplant and Chimeric Antigen Receptor Therapy (CAR-T): Implementation of an Early Nurse Practitioner-Led Primary Palliative Care Intervention.

Abigail G Cohen, Dana Kramer, Kathryn Mazzarella, Megan H Scott, Mia Szkolnicki, Alli Tucker, Kelley Qualters, Miguel-Angel Perales, Chelsea Brooklyn, Andrew S Epstein and 2 more

Abstract read
In one paragraph

Article in Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Abigail G CohenAbigail G. Cohen, MSc, ANP-BC, AOCNP, BMTCN, is a Nurse Practitioner, BMT/CAR-T Survivorship Program, Memorial Sloan Kettering Cancer Center, New York, NY.
Dana KramerDana Kramer, MSc, ANP-BC, is a Nurse Practitioner, Supportive Care Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Kathryn MazzarellaKathryn Mazzarella, MSc, AGPCNP-BC, AOCNP, is a Nurse Practitioner, Outpatient BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Megan H ScottMegan H. Scott, MSc, ANP-BC, AOCNP, BMTCN, is a Nurse Practitioner, Outpatient BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Mia SzkolnickiMia Szkolnicki, MSc, AGPCNP-BC, OCN, is a Nurse Practitioner, Outpatient BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Alli TuckerAlli Tucker, MSc, AGCNP-BC, OCN, is a Nurse Practitioner, Outpatient BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Kelley QualtersKelley Qualters, MSc, AGPCNP-BC, AHPCN, is a Nurse Practitioner, Supportive Care Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Miguel-Angel PeralesMiguel-Angel Perales, MD, is a Chief, Attending Physician and Member, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, NY; and Department of Medicine, Weill Cornell Medical College, New York, NY.
Chelsea BrooklynChelsea Brooklyn, BSc, is a Health Operations Leader, Outpatient BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Andrew S EpsteinAndrew S. Epstein, MD, is a Attending Physician, Gastrointestinal Oncology and Supportive Care Services, Memorial Sloan Kettering Cancer Center, New York, NY.
Judith E NelsonJudith E. Nelson, MD, is a Attending Physician, Supportive Care Service, Memorial Sloan Kettering Cancer Center, New York, NY; and Department of Medicine, Weill Cornell Medical College, New York, NY.
Nicole LestrangeNicole Lestrange, DNP, ANP-BC, AOCNP, is an Associate Director, Advanced Practice Providers, Division of Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Patients undergoing hematopoietic stem cell transplant and chimeric antigen receptor-T cell therapy face significant uncertainty, distress, risk of serious treatment-related complications, and disease relapse. Although palliative care and advance care planning offer clear benefits, both remain underutilized or delayed in this patient population. To address this gap, a nurse practitioner (NP)-led primary palliative care intervention was implemented in the outpatient Bone Marrow Transplant and Cellular Therapy Services at a comprehensive cancer center. This paper provides an overview of the program model, involving NP-led health-related values and care preferences discussions with patients and their families. This highlights the pivotal role of NPs in delivering primary palliative care by integrating values-based discussions into routine oncology practice. Future goals include evaluating the intervention's impact on patient and caregiver outcomes, clinician understanding, care alignment with patient's goals, advance directive completion, and high-intensity care at the end of life.

Indexed as

Nurse PractitionersPalliative CareStem Cell TransplantationAdultFemaleHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedTransplantation, AutologousTransplantation, Homologousadvance care planningchimeric antigen receptor therapyhealth-related valueshematopoietic cell transplantnurse practitioneroncology advanced practice nursespatient-centered careprimary palliative care

Identifiers

PMID40845273
PMCPMC12380123

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.