Evidence map›Paper›PMID 40845246›Full record

ArticleACS macro letters2025

Sequence-Controlled Neutral-Ionic Multiblock-Like Copolymers through Switchable PIESA in a One-Pot Approach.

Fabian H Sobotta, Bas G P van Ravensteijn, Ilja K Voets

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS macro letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fabian H SobottaLaboratory of Self-Organizing Soft Matter, Department of Chemical Engineering and Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands.ORCID 0000-0002-6213-8051
Bas G P van RavensteijnDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Science for Life, Faculty of Science, Utrecht University, P.O. Box 80082, 3508 TB, Utrecht, The Netherlands.ORCID 0000-0001-9024-3927
Ilja K VoetsLaboratory of Self-Organizing Soft Matter, Department of Chemical Engineering and Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands.ORCID 0000-0003-3543-4821

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Control over the composition and sequence of synthetic copolymers represents one of the most challenging targets in modern polymer science, in particular, for the labor- and time-consuming preparation of copolymers bearing ionic moieties. Though so far primarily focused on the assembly of coacervate nanostructures, we leverage polymerization-induced electrostatic self-assembly (PIESA) to achieve control over the composition and sequence of neutral-ionic copolymers and create complex chain topologies from equimolar mixtures of neutral and ionic monomers in a direct, one-pot process in aqueous solution. We are making use of the selective recruitment of charged over neutral monomers on an oppositely charged template to modulate monomer reactivities

Identifiers

PMID40845246
PMCPMC12444980

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.