ArticlePloS one2025
Assessing antibiotics consumption, use and outcomes in a Yemeni tertiary hospital: A prospective cross-sectional study.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Global under- and overprescribing of drugs-a scoping review.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntibiotics (ABs) have saved countless lives, but their misuse has led to a serious problem: antibiotic resistance. This growing phenomenon poses serious threats to public health worldwide, as it could make treating infections significantly more difficult in the future.
objectivesThis study aimed to investigate antibiotic consumption and use patterns in a tertiary hospital in Sana'a, Yemen, by comparing Prescribed Daily Doses (PDD) to Defined Daily Doses (DDD), and identifying factors associated with antibiotic misuse and its impact on patient outcomes.
methodsA prospective cross-sectional study was conducted among adult inpatients in a tertiary hospital in Sana'a, Yemen over two months (January 12 to March 11, 2024), involving 597 patients. Data on antibiotic prescriptions, patient demographics, and outcomes were collected.
resultsA high prevalence of antibiotic use was observed (92.5%), with a notable proportion of prescriptions from the "Watch" category (56.7%). Significant PDD-DDD deviations were common, encompassing both overuse (36.8%) and underuse (63.2%). Factors associated with antibiotic deviations included patient age (26-44 years), gender (female), and ward type (private). The most commonly prescribed antibiotics were Ceftriaxone (33.6%), Metronidazole (21.8%), Vancomycin (6.0%), Levofloxacin (4.9%), Imipenem/Cilastatin (4.7%), and Moxifloxacin (3.6%). Notable deviations from DDD were observed for Levofloxacin (overuse by 28%), Imipenem/Cilastatin (underuse by 40.5%), and other agents. Antibiotic misuse was associated with longer hospital stays and less favorable discharge outcomes.
conclusionThe study found an alarmingly high prevalence of antibiotic use and excessive consumption, with both overuse and underuse patterns observed, underscoring the need for effective regulatory interventions and improved antibiotic stewardship in Yemen.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.