ReviewPLoS pathogens2025
Emerging challenges for mosquito-borne disease control and the promise of symbiont-based transmission-blocking strategies.
Review in PLoS pathogens, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of natural predators, microbial bioinsecticides, and plant-based bioinsecticides to reduce mosquito-borne disease burden: a systematic review.Journal of medical entomology · 2026Pooled it
- Mosquito-based malaria control through genetic, microbial and immunological innovations.Nature reviews. Microbiology · 2026Review
- Host range ofMicrobiology spectrum · 2026Article
- Evaluating the impact of the 'Four Pest-Free Villages' program on mosquito-borne disease control in Zhejiang Province, China: a cross-sectional study on knowledge, attitudes, and practices.Infectious diseases of poverty · 2026Article
- Evaluating AI-based mosquito monitoring technologies: a field study in Zhejiang Province, 2025.Frontiers in veterinary science · 2026Article
- Transplant of cryopreserved mosquito gut microbiota reveals strain-specific patterns of microbial acquisition and assembly.ISME host microbe · 2026Article
- Poly(I:C) and R848 adjuvants elicit sizeable humoral immunity to liver stage malaria antigens.Frontiers in immunology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Mosquitoes serve as vectors for a variety of pathogens that cause life-threatening diseases, such as malaria, dengue, Zika, and yellow fever. With the rise of antimalarial drug resistance and a lack of therapeutics or prophylactics for dengue and Zika, current disease control strategies rely heavily on mosquito population management. However, the effectiveness of conventional approaches is increasingly compromised, highlighting an urgent need for innovative tools to combat mosquito-borne diseases. One promising strategy for blocking the transmission of these diseases is to populate mosquitoes with anti-pathogen gut symbionts. Here, we discuss the major challenges facing current mosquito-borne disease control efforts and explore how mosquito gut microbiota-based control strategies may address them. We highlight recent advances that may accelerate field applications and offer perspectives on future directions and the translational potential of symbiont-based strategies for mitigating mosquito-borne disease transmission.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.