Evidence map›Paper›PMID 40844808›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Coordinated actions of NLR-assembled and glutamate receptor-like calcium channels in plant effector-triggered immunity.

Junli Wang, Xinhua Sun, Fei Xiong, Dmitry Lapin, Tak Lee, Sergio Martin-Ramirez, Anna Prakken, Qiaochu Shen, Jaqueline Bautor, Takaki Maekawa and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Molecular mechanisms of plant NLR activation and signalling.The Plant journal : for cell and molecular biology · 2026
    Review
  4. QnAs with Jane E. Parker.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Review
  6. Coordinated actions of NLR-assembled and glutamate receptor-like calcium channels in plant effector-triggered immunity.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Junli Wang *Department of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne 50829, Germany.ORCID 0000-0001-8825-3894
Xinhua Sun *Department of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne 50829, Germany.ORCID 0000-0001-8687-2528
Fei XiongDepartment of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne 50829, Germany.
Dmitry LapinDepartment of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne 50829, Germany.
Tak LeeDepartment of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne 50829, Germany.
Sergio Martin-RamirezDepartment of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne 50829, Germany.ORCID 0000-0002-3297-1704
Anna PrakkenInstitute for Plant Sciences, University of Cologne, Cologne, North Rhine-Westphalia 50674, Germany.
Qiaochu ShenInstitute for Plant Sciences, University of Cologne, Cologne, North Rhine-Westphalia 50674, Germany.
Jaqueline BautorDepartment of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne 50829, Germany.
Takaki MaekawaInstitute for Plant Sciences, University of Cologne, Cologne, North Rhine-Westphalia 50674, Germany.ORCID 0000-0003-4547-5539
Jane E ParkerDepartment of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne 50829, Germany.ORCID 0000-0002-4700-6480

Funding

Deutsche Forschungsgemeinschaft (DFG) SFB-1403-414786233
6 · The paper itself

Abstract

The plant immune system utilizes nucleotide-binding/leucine-rich repeat (NLR) proteins to detect pathogen virulence factors (effectors) inside host cells and transduce recognition to rapid defense. In dicotyledenous plants, pathogen activated Toll-like/interleukin-1 receptor-containing NLRs (TNLs) establish a signaling network of enhanced susceptibility 1 (EDS1)-family dimers with RPW8-type coiled-coil (CC

Indexed as

Calcium ChannelsNicotianaNLR ProteinsPlant ImmunityPlant ProteinsArabidopsisCell DeathDisease ResistanceGene Expression Regulation, PlantProtein DomainsSignal TransductionCalcium ChannelsNLR ProteinsPlant Proteinscalciumeffector-triggered immunityglutamate receptor–likeNicotiana benthamianaN requirement gene 1

Identifiers

PMID40844808
PMCPMC12415192

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.