Evidence map›Paper›PMID 40844589›Full record

ArticleVeterinary medicine and science2025

Impact of Gestational and Lactational Live Yeast Supplementation to Sows on Litter Performance, Colostrum and Milk Proteome Profiles.

Yuechi Fu, Venkatesh P Thirumalaikumar, Theresa M Casey, Timothy A Johnson, Jun Xie, Olayiwola Adeola, Kolapo M Ajuwon

Abstract read
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuechi FuDepartment of Animal Sciences, Purdue University, West Lafayette, USA.ORCID https://orcid.org/0000-0001-5989-844X
Venkatesh P ThirumalaikumarPurdue Proteomics Facility, Bindley Bioscience Center, Purdue University, West Lafayette, USA.
Theresa M CaseyDepartment of Animal Sciences, Purdue University, West Lafayette, USA.
Timothy A JohnsonDepartment of Animal Sciences, Purdue University, West Lafayette, USA.
Jun XieDepartment of Statistics, Purdue University, West Lafayette, USA.
Olayiwola AdeolaDepartment of Animal Sciences, Purdue University, West Lafayette, USA.
Kolapo M AjuwonDepartment of Animal Sciences, Purdue University, West Lafayette, USA.ORCID https://orcid.org/0000-0002-5523-7457

Funding

National Institute of Food and Agriculture
6 · The paper itself

Abstract

This study investigated the effects of dietary live yeast (LY) supplementation to sows during late gestation and lactation on sow and litter performance indices and colostrum and milk proteome profiles. On Day 77 of gestation, 20 sows were allotted to each of 2 dietary treatments: without (control) or with LY (Saccharomyces cerevisiae) supplementation at 0.05% of diet during gestation and 0.1% during lactation. Sow performance was recorded on Days 77 and 112 of gestation and Day 19 of lactation. Litter characteristics were recorded at birth and weaning. Colostrum and milk samples were collected on Days 0, 10 and 18 of lactation for shotgun proteomic analysis. Results showed that there was a higher abundance of immune-associated proteins such as Ig-like domain-containing protein and complement proteins (Complement C8 alpha chain and C1q domain-containing proteins) in the colostrum and IgG heavy chain in Day 10 milk of LY sows than control sows (p < 0.05), whereas the abundance of prostaglandin D synthase was greater in D10 milk of control sows than LY sows (p < 0.05). Additionally, milk fat globule EGF and factor V/VIII domain-containing protein and Niemann-Pick C2 were found to be more abundant in both Days 10 and 18 milk samples from LY sows (p < 0.05). Overall, these results showed that dietary gestational and lactational LY supplementation increased the abundance of immune-associated proteins in colostrum and proteins involved in lipid uptake and processing in mature milk.

Indexed as

ColostrumMilkProteomeSaccharomyces cerevisiaeSus scrofaAnimal FeedAnimalsDietDietary SupplementsFemaleLactationPregnancyProteomecolostrumlive yeastmaternal transfermilkpigletproteome

Identifiers

PMID40844589
PMCPMC12372606

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.