SynthesisLasers in medical science2025
Effects of transcranial photobiomodulation in cerebral circulation and brain neural oscillations: a systematic review.
Synthesis in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Single-Exposure Prophylactic Transcranial Nano-Pulsed Laser Therapy Promotes Functional Resilience Following Mild Blast-Induced Neurotrauma.International journal of molecular sciences · 2026Article
- Application of non-invasive transcranial photobiomodulation in ischemic stroke: Mechanisms and current insights.iScience · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcranial photobiomodulation (tPBM) uses the light of lasers or light-emitting diodes to modulate and improve brain function. In this study, the use of tPBM for improving cerebral circulation and modulating brain neural oscillations has been systematically reviewed to determine the useful parameters of tPBM and the grade of its practical recommendation. The PROSPERO code "CRD42023393544". "Google scholar", "Pub Med", "Scopus" and "science direct" online databases were searched based on Preferred Reporting Items for Systematic Reviews and meta-analyses (PRISMA) guidelines. Search keywords were "low level laser therapy AND cerebral circulation" OR "photobiomodulation therapy AND cerebral circulation" OR "low level laser therapy AND brain neural oscillation" OR "photobiomodulation therapy AND brain neural oscillations". Reviews, preprints, non-transcranial PBM, patents, unpublished articles, non-English articles, case reports and non-related articles were excluded. Forty-five studies published from January 2009 to May 2024, including 18 animal studies and 27 human studies, were included. 808 (810) nanometer (nm) and 1064 nm wavelengths, power density of 250 mW/cm
Indexed as
Identifiers
40844561What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.