ArticleJACC. Asia2025
Characteristics of Effective Antitachycardia Pacing for Ventricular Tachycardia: The Importance of True Septal Lead Position.
Article in JACC. Asia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Timely transmission of alert events and prompt management of ventricular arrhythmias using app-based remote monitoring in a patient with a cardiac implantable electronic device.HeartRhythm case reports · 2026Article
- Successful termination of ventricular tachycardia by intrinsic antitachycardia pacing delivered from a left bundle branch area pacing lead: a case report.European heart journal. Case reports · 2026Article
- Smartphone-Based Remote Monitoring for Cardiac Implantable Electronic Devices: Transmission Performance and Early Alert Responsiveness.JACC. Asia · 2026Article
- Antitachycardia Pacing for Fast Scar-Mediated Ventricular Tachycardia Across Non-Ischemic Cardiomyopathies: A Case Series.International medical case reports journal · 2026Article
- Is Septal Pacing Effective for Antitachycardia Pacing of Implantable Cardioverter-Defibrillator?JACC. Asia · 2025Article
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntitachycardia pacing (ATP) has a potential benefit for shock reduction of implantable cardioverter-defibrillator (ICD) recipients; however, its clinical utility and characteristics are unknown.
objectivesThis study aims to extract characteristics leading to a high ventricular tachycardia (VT) termination rate of ATP.
methodsPatients who had a history of ≥1 ATP treatment episode from ICD or cardiac resynchronization therapy-defibrillator (CRTD) devices were included. All ATP treatments wherein intracardiac electrograms could be traced were reviewed. Two endpoints of VT termination were defined: type-I break (termination with 0-1 beat) and clinical endpoint of termination (≤5 beats). We assessed the characteristics associated with a high success rate of ATP using the logistic regression generalized estimating equation method.
resultsOf 756 recipients using high-power devices, 1,468 treatment episodes in 119 patients were analyzed. The VT rate of <188 beats/min (vs ≥188 beats/min), CRTD (vs ICD), and true septum right ventricular lead position were significantly associated with high success rate of type-I break termination (generalized estimating equation success rate: 78.7% vs 64.7%, P = 0.011; 80.1% vs 66.5%, P = 0.021; and 79.8% vs 60.5%, P = 0.023, respectively). True septum lead position and slow VT were also independently associated with successful termination with clinical endpoint. The termination rate was highest in the right ventricular true septum position across all positions at both endpoints. The pacing QRS interval was significantly shorter in the septum group than in the nonseptum group (166.2 ± 21.9 ms vs 198.7 ± 26.5 ms; P < 0.001).
conclusionsTrue septum lead position, in addition to slow VT and CRTD, may be key to high ATP termination success.
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