Evidence map›Paper›PMID 40844370›Full record

GuidelineThyroid : official journal of the American Thyroid Association2025

2025 American Thyroid Association Management Guidelines for Adult Patients with Differentiated Thyroid Cancer.

Matthew D Ringel, Julie Ann Sosa, Zubair Baloch, Lindsay Bischoff, Gary Bloom, Gregory A Brent, Pamela L Brock, Roger Chou, Robert R Flavell, Whitney Goldner and 10 more

Erratum issued Registry-linked trialAbstract readPractice Guideline
In one paragraph

Guideline in Thyroid : official journal of the American Thyroid Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07239674 (Desiccated Thyroid Extract Combined With Levothyroxine for TSH Suppression Therapy in Intermediate-to-High Risk Differentiated Thyroid Cancer After Surgery), which is not on this map. Cited by 418 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
418citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07239674 phase3not yet recruitingnot on this map

Desiccated Thyroid Extract Combined With Levothyroxine for TSH Suppression Therapy in Intermediate-to-High Risk Differentiated Thyroid Cancer After Surgery: A National Multicenter, Open-Label, Randomized Controlled Trial

TypeinterventionalSponsorWest China HospitalRan2025 to 2028Enrolled646ConditionsIntermediate-to-High Risk Differentiated Thyroid CancerArmsdesiccated thyroid extract (DTE)+levothyroxine (L-T4)
3 · Its place in the literature

Who cites it

418 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. The Role of Thyroidectomy in the Management of Thyroglossal Duct Carcinoma: A Systematic Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Identification and assessment ofOncology letters · 2026
    Article
  11. Article
  12. Article
  13. JCEM case reports · 2026
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

358 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
    2025
5 · Who and what money

Authors and funding

20 authors.

Matthew D RingelDepartment of Molecular Medicine and Therapeutics, The Ohio State University College of Medicine and Comprehensive Cancer Center, Columbus, Ohio, USA.
Julie Ann SosaDepartment of Surgery, University of California San Francisco (UCSF), San Francisco, California, USA.
Zubair BalochDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lindsay BischoffDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Gary BloomThyCa: Thyroid Cancer Survivors' Association, Inc., Olney, Maryland, USA.
Gregory A BrentDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, USA.ORCID 0000-0002-4638-6645
Pamela L BrockDivision of Human Genetics, Department of Internal Medicine, The Ohio State University College of Medicine, Wexner Medical Center, and Comprehensive Cancer Center, Columbus, Ohio, USA.
Roger ChouDepartment of Medical Informatics and Clinical Epidemiology and Department of Medicine, Oregon Health and Science University, Portland, Oregon, USA.
Robert R FlavellDepartments of Radiology and Biomedical Imaging and Pharmaceutical Chemistry, University of California, San Francisco, California, USA.
Whitney GoldnerDepartment of Medicine, Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Denver, Colorado, USA.
Elizabeth G GrubbsDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Megan HaymartDepartment of Medicine, Division of Metabolism, Endocrinology, and Diabetes. University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-1083-1575
Steven M LarsonDepartment of Radiology, Molecular Imaging and Therapy Service, Memorial Loan Kettering Cancer Center. New York, New York, USA.
Angela M LeungDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, USA.ORCID 0000-0001-8935-9332
Joseph R OsborneDivision of Molecular Imaging and Therapeutics, Department of Radiology, Weill Cornell Medicine, New York, New York, USA.
John A RidgeDepartment of Surgical Oncology, Fox Chase Cancer Center, Lewis Katz School of Medicine, Temple University Philadelphia, Philadelphia, Pennsylvania, USA.
Bruce RobinsonDepartment of Endocrinology, Royal North Shore Hospital and University of Sydney, Sydney, Australia.
David L StewardDepartment of Otolaryngology - Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0003-2680-8692
Ralph P TufanoDivision of Otolaryngology-Head and Neck Surgery, Sarasota Memorial Health Care System, The Florida State University College of Medicine, Sarasota, Florida, USA.
Lori J WirthDepartment of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-2629-2289

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Daniel G. Stover · 1985 to 2026
$132.3M
NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Thyroid NeoplasmsAdultDisease ManagementHumansSocieties, MedicalUnited Statesactive surveillanceradioactive iodinetargeted therapythyroglobulinthyroid cancerthyroidectomy

Identifiers

PMID40844370
PMCPMC13090833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.