Observational studyJournal of pediatric gastroenterology and nutrition2025
Bowel habits in preterm infants: Observations from the first 2 weeks of life.
Observational study in Journal of pediatric gastroenterology and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Bowel habits in preterm infants: Observations from the first 2 weeks of life.Journal of pediatric gastroenterology and nutrition · 2025Observational
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectivesUniform descriptions of normal preterm infant bowel habits are lacking, causing ambiguity in identifying abnormal bowel habits in this population. This study examines preterm infants' bowel habits and their association with maternal and infant factors in the first 2 weeks of life.
methodsAn observational study included infants with a gestational age (GA) < 31 weeks from January to September 2021. From infant and maternal medical records, information on prenatal events, 2 weeks of bowel habit observations, enteral feeding, and laxative treatment was obtained. Extremely preterm infants (EPI) and very preterm infants (VPIs) were defined as GA < 28 weeks and GA ≥ 28 weeks, respectively.
resultsOf the 93 infants, 53 (57%) were included, and 37 (70%) were EPI. EPI received first enteral feeds at a median of 5 h after birth versus 2 h after birth in VPI (p < 0.01). EPI passed their first meconium at a median of 30 h (interquartile range [IQR] 12-49 h) after birth versus 26 h in VPI (IQR: 10-40, p = 0.2). In 21% of all infants, saline enemas were used to induce the passage of meconium. In 41% of EPIs (n = 15) laxatives were initiated before 2 weeks of age. Stool frequency varied from 0 to 9 stools daily, and prenatal events did not affect bowel habits.
conclusionThis study provides a day-by-day description of bowel habits, enteral feeds, and laxative treatment but shows no associations with prenatal events in preterm infants. For future research, we recommend implementing homogeneous observation tools to enable comparison between studies.
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