Evidence map›Paper›PMID 40843986›Full record

ArticleActa physiologica (Oxford, England)2025

Magnetic Resonance Cartography of Renal Tubule Volume Fraction During Diuretic Intervention.

Ehsan Tasbihi, Thomas Gladytz, Jason M Millward, Kathleen Cantow, Erdmann Seeliger, Thoralf Niendorf

Abstract read
In one paragraph

Article in Acta physiologica (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ehsan TasbihiMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.), Berlin, Germany.ORCID https://orcid.org/0000-0002-4190-7202
Thomas GladytzMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.), Berlin, Germany.ORCID https://orcid.org/0000-0003-1072-0098
Jason M MillwardMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.), Berlin, Germany.ORCID https://orcid.org/0000-0003-4484-2798
Kathleen CantowInstitute of Translational Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-3907-6315
Erdmann SeeligerInstitute of Translational Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-5685-8044
Thoralf NiendorfMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.), Berlin, Germany.ORCID https://orcid.org/0000-0001-7584-6527

Funding

Deutsche Forschungsgemeinschaft NI 532/27-1
6 · The paper itself

Abstract

aimThe renal tubular volume fraction (TVF) fluctuates under physiological conditions, and is altered in several renal diseases. Tools that enable noninvasive assessment of TVF are currently lacking. Magnetic Resonance (MR) TVF cartography is a novel approach for unraveling renal (patho-)physiology. Here, we employ MR-TVF cartography to monitor changes in response to the diuretic furosemide, and examine its role for the interpretation of renal oxygenation assessed by mapping the MRI relaxation time T

methodsIn anesthetized rats (n = 7) the MRI relaxation times T

resultsFurosemide induced changes in renal MRI and NIRS parameters relative to baseline: TVF

conclusionMR-TVF cartography is highly relevant for elucidating mechanisms of renal (patho-)physiology, including the role of renal oxygenation assessed by MRI mapping of renal T

Indexed as

DiureticsFurosemideKidney TubulesMagnetic Resonance ImagingAnimalsMaleRatsRats, Sprague-DawleyDiureticsFurosemidefurosemidekidneyMRItubule systemtubule volume fraction

Identifiers

PMID40843986
PMCPMC12371858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.